Literature DB >> 26816277

Postoperative Protocol in the Prevention of Fragility Fractures in Patients with Osteoporosis-Related Fractures.

Sebastian Seitz1, F Timo Beil, Florian Barvencik, Christoph von Domarus, Johannes M Rueger, Michael Amling2.   

Abstract

Osteoporosis is a multifactorial disorder that requires advanced diagnostic evaluation tools. It should not be considered to be an inevitable disease entity or as a logical consequence of the physiological ageing process. Osteoporosis can be diagnosed and - more importantly - properly treated. It is therefore incomprehensible that most of the patients with diagnosed osteoporosis do not receive a specific pharmacotherapeutic treatment. Since orthopedic trauma surgeons most often see a patient with an osteoporosis-associated fracture on a first-hand basis, they, after providing adequate treatment of the fracture, must play a key role in initiating the primary diagnostics and therapy according to national or international guidelines for patients with previous osteoporotic fractures. Treatment should be closely coordinated with general practitioners so that a continuation of the therapy initiated in the hospital can be guaranteed. Basic measures for fracture prevention, including dietary supplements of calcium and vitamin D, should be recommended and implemented for all patients, whereas only those patients with the diagnosis of a manifest osteoporosis should receive a specific pharmacotherapy. Antiresorptive and anabolic drugs that are licensed for the treatment of men or postmenopausal women with osteoporosis have been shown to effectively reduce the incidence of vertebral and non-vertebral fractures. An evaluation of the treatment efficiency should also be performed, such as routine clinical re-evaluation and the measuring of the bone mineral density by dual X-ray absortiometry, every 18-24 months after the initiation of the pharmacotherapy.

Entities:  

Keywords:  Dual X-ray absorptiometry; Fracture; Guidelines; Osteoporosis; Tertiary prophylaxis

Year:  2008        PMID: 26816277     DOI: 10.1007/s00068-008-8205-7

Source DB:  PubMed          Journal:  Eur J Trauma Emerg Surg        ISSN: 1863-9933            Impact factor:   3.693


  23 in total

Review 1.  The World Health Organization analgesic ladder.

Authors:  Elissa Miller
Journal:  J Midwifery Womens Health       Date:  2004 Nov-Dec       Impact factor: 2.388

Review 2.  Clinical practice. Osteoporosis in men.

Authors:  Peter R Ebeling
Journal:  N Engl J Med       Date:  2008-04-03       Impact factor: 91.245

3.  Epidemiology, treatment and costs of osteoporosis in Germany--the BoneEVA Study.

Authors:  B Häussler; H Gothe; D Göl; G Glaeske; L Pientka; D Felsenberg
Journal:  Osteoporos Int       Date:  2006-09-19       Impact factor: 4.507

Review 4.  Recombinant full-length parathyroid hormone (1-84).

Authors:  Marit D Moen; Lesley J Scott
Journal:  Drugs       Date:  2006       Impact factor: 9.546

5.  When should the doctor order a spine X-ray? Identifying vertebral fractures for osteoporosis care: results from the European Prospective Osteoporosis Study (EPOS).

Authors:  Stephen Kaptoge; Gabi Armbrecht; Dieter Felsenberg; Mark Lunt; Terence W O'Neill; Alan J Silman; Jonathan Reeve
Journal:  J Bone Miner Res       Date:  2004-09-07       Impact factor: 6.741

6.  Bone mineralization defects and vitamin D deficiency: histomorphometric analysis of iliac crest bone biopsies and circulating 25-hydroxyvitamin D in 675 patients.

Authors:  Matthias Priemel; Christoph von Domarus; Till Orla Klatte; Steffen Kessler; Julia Schlie; Simon Meier; Nils Proksch; Frederic Pastor; Clemens Netter; Thomas Streichert; Klaus Püschel; Michael Amling
Journal:  J Bone Miner Res       Date:  2010-02       Impact factor: 6.741

7.  Changes in bone mineral density of the proximal femur and spine with aging. Differences between the postmenopausal and senile osteoporosis syndromes.

Authors:  B L Riggs; H W Wahner; E Seeman; K P Offord; W L Dunn; R B Mazess; K A Johnson; L J Melton
Journal:  J Clin Invest       Date:  1982-10       Impact factor: 14.808

8.  Outcome of osteoporotic pelvic fractures: an underestimated severity. Survey of 60 cases.

Authors:  Véronique Breuil; Christian Hubert Roux; Jean Testa; Christine Albert; Madleen Chassang; Olivier Brocq; Liana Euller-Ziegler
Journal:  Joint Bone Spine       Date:  2008-05-12       Impact factor: 4.929

9.  BMD at multiple sites and risk of fracture of multiple types: long-term results from the Study of Osteoporotic Fractures.

Authors:  Katie L Stone; Dana G Seeley; Li-Yung Lui; Jane A Cauley; Kristine Ensrud; Warren S Browner; Michael C Nevitt; Steven R Cummings
Journal:  J Bone Miner Res       Date:  2003-11       Impact factor: 6.741

10.  Efficacy and tolerability of intravenous ibandronate injections in postmenopausal osteoporosis: 2-year results from the DIVA study.

Authors:  John A Eisman; Roberto Civitelli; Silvano Adami; Edward Czerwinski; Chris Recknor; Richard Prince; Jean-Yves Reginster; Mone Zaidi; Dieter Felsenberg; Claire Hughes; Nicole Mairon; Daiva Masanauskaite; David M Reid; Pierre D Delmas; Robert R Recker
Journal:  J Rheumatol       Date:  2008-02-01       Impact factor: 4.666

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  1 in total

1.  Focus on Skeletal Bone Diseases - Osteoporosis and Paget's Disease of Bone.

Authors: 
Journal:  Eur J Trauma Emerg Surg       Date:  2008-12       Impact factor: 3.693

  1 in total

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