Literature DB >> 26816276

Current Aspects of Fragility Fracture Repair.

Stefan Grote1, Wolfgang Boecker, Wolf Mutschler, Matthias Schieker2,3.   

Abstract

Due to the demographic developments worldwide, fragility fractures represent an increasing problem for the public health system. The risk of developing osteoporosis increases with age and is relatively higher in women and in the Caucasian population. The stability of bone is reduced because of accentuation of the normal loss of bone mass in ageing, leading to an increased susceptibility to fracture with an increased rate of complications after surgical stabilization. Due to this, the orthopedic surgeon has to assess the quality of the bone during preoperative planning and select the implants and postoperative care accordingly to achieve the best. Over the last 10 years fixed locking implants have been introduced into clinical practice. These represent a new type of angle stable fixation devices that address the mechanical instability between bone and implant. The novel problems associated with this device are due to higher cut-out rates when the bone structure is altered and mass is reduced. The developments in joint replacement have also resulted in longer standing times and lower complication rates with immediate fullweight-bearing after implantation. However, to date, little is known about the mechanisms of fracture healing in osteoporosis or fragility fractures. One future approach may be in supporting biological fracture healing by regenerative therapies using growth hormones and/or (stem) cells. The most frequent initial clinical symptom of osteoporosis is a fracture without a relevant trauma. At this stage, the trauma surgeon should initiate diagnostic procedures, treatment of osteoporosis and tertiary prevention according to the European guidelines. Ultimately, all female patients older than 50 years and all male patients older than 60 years with fractures should be assessed and treated for bone quality. Orthogeriatric specialists or interdisciplinary orthogeriatric teams should initiate a specific surgical treatment followed by early rehabilitation in order to allow the elderly patient to return to daily living as soon as possible.

Entities:  

Keywords:  Fixed angle implants; Fracture fixation; Fragility fracture; Orthogeriatric; Osteoporosis

Year:  2008        PMID: 26816276     DOI: 10.1007/s00068-008-8207-5

Source DB:  PubMed          Journal:  Eur J Trauma Emerg Surg        ISSN: 1863-9933            Impact factor:   3.693


  33 in total

1.  Vertebroplasty for osteoporotic vertebral fracture.

Authors:  Robert G W Lambert; Kamran Golmohammadi
Journal:  BMJ       Date:  2008-06-07

Review 2.  Tissue engineering for bone defect healing: an update on a multi-component approach.

Authors:  Inga Drosse; Elias Volkmer; Rodolfo Capanna; Pietro De Biase; Wolf Mutschler; Matthias Schieker
Journal:  Injury       Date:  2008-09       Impact factor: 2.586

Review 3.  The potential of gene therapy for fracture healing in osteoporosis.

Authors:  M Egermann; E Schneider; C H Evans; A W Baltzer
Journal:  Osteoporos Int       Date:  2005-01-15       Impact factor: 4.507

4.  Guidelines for diagnosis and management of osteoporosis. The European Foundation for Osteoporosis and Bone Disease.

Authors:  J A Kanis; P Delmas; P Burckhardt; C Cooper; D Torgerson
Journal:  Osteoporos Int       Date:  1997       Impact factor: 4.507

Review 5.  Treatment strategies for proximal femur fractures in osteoporotic patients.

Authors:  Felix Bonnaire; Henry Zenker; Christoph Lill; Andreas T Weber; Berend Linke
Journal:  Osteoporos Int       Date:  2004-10-16       Impact factor: 4.507

6.  A multicenter, prospective, randomized, controlled trial of open reduction--internal fixation versus total elbow arthroplasty for displaced intra-articular distal humeral fractures in elderly patients.

Authors:  Michael D McKee; Christian J H Veillette; Jeremy A Hall; Emil H Schemitsch; Lisa M Wild; Robert McCormack; Bertrand Perey; Thomas Goetz; Mauri Zomar; Karyn Moon; Scott Mandel; Shirlet Petit; Pierre Guy; Irene Leung
Journal:  J Shoulder Elbow Surg       Date:  2008-09-26       Impact factor: 3.019

7.  Effects of extended outpatient rehabilitation after hip fracture: a randomized controlled trial.

Authors:  Ellen F Binder; Marybeth Brown; David R Sinacore; Karen Steger-May; Kevin E Yarasheski; Kenneth B Schechtman
Journal:  JAMA       Date:  2004-08-18       Impact factor: 56.272

Review 8.  Bone alterations during HIV infection.

Authors:  Elisa De Crignis; Laura Cimatti; Marco Borderi; Davide Gibellini; Maria Carla Re
Journal:  New Microbiol       Date:  2008-04       Impact factor: 2.479

Review 9.  Do We need to include osteoporosis in today's classification of distal radius fractures?

Authors:  Mark Kettler; Volker Kuhn; Matthias Schieker; Charles P Melone
Journal:  J Orthop Trauma       Date:  2008-09       Impact factor: 2.512

Review 10.  Plate fixation of osteoporotic fractures of the distal radius.

Authors:  Chaitanya S Mudgal; Jesse B Jupiter
Journal:  J Orthop Trauma       Date:  2008-09       Impact factor: 2.512

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  2 in total

1.  [Treatment results after cemented hemiprosthesis for care of unstable pertrochanteric femoral fractures in the elderly].

Authors:  S Grote; F Stegmeyer; V Bogner; P Biberthaler; W Mutschler
Journal:  Unfallchirurg       Date:  2012-03       Impact factor: 1.000

2.  Focus on Skeletal Bone Diseases - Osteoporosis and Paget's Disease of Bone.

Authors: 
Journal:  Eur J Trauma Emerg Surg       Date:  2008-12       Impact factor: 3.693

  2 in total

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