Literature DB >> 26815549

Is computed tomography necessary to determine liver injury in pediatric trauma patients with negative ultrasonography?

U Kaya1, U Y Çavuş2, M E Karakılıç3, A B Erdem4, K Aydın2, B Işık1, S Abacıoğlu1, F Büyükcam5.   

Abstract

PURPOSE: Abdominal trauma is the third most common cause of all trauma-related deaths in children. Liver injury is the second most common, but the most fatal injury associated with abdomen trauma. Because the liver enzymes have high sensitivity and specificity, the use of tomography has been discussed for accurate diagnosis of liver injury.
METHODS: Our study was based on retrospective analyses of hemodynamically stabil patients under the age of 18 who were admitted to the emergency department with blunt abdominal trauma.
RESULTS: Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels were significantly higher as a result of liver injury. In the patients whose AST and ALT levels were lower than 40 IU/L, no liver injury was observed in the contrast-enhanced computed tomography (CT). No liver injury was detected in the patients with AST levels lower than 100 IU/L. Liver injury was detected with contrast-enhanced CT in only one patient whose ALT level was lower than 100 IU/L, but ultrasonography initially detected liver injury in this patient.
CONCLUSIONS: According to our findings, abdominal CT may not be necessary to detect liver injury if the patient has ALT and AST levels below 100 IU/L with a negative abdominal USG at admission and during follow-up.

Entities:  

Keywords:  Liver enzyme; Liver injury; Pediatric abdominal trauma; Ultrasonography

Year:  2013        PMID: 26815549     DOI: 10.1007/s00068-013-0322-2

Source DB:  PubMed          Journal:  Eur J Trauma Emerg Surg        ISSN: 1863-9933            Impact factor:   3.693


  35 in total

1.  Repeat abdominal computed tomography scans after pediatric blunt abdominal trauma: missed injuries, extra costs, and unnecessary radiation exposure.

Authors:  Steven H Cook; Julia R Fielding; J Duncan Phillips
Journal:  J Pediatr Surg       Date:  2010-10       Impact factor: 2.545

Review 2.  Systematic review and meta-analysis of emergency ultrasonography for blunt abdominal trauma.

Authors:  D Stengel; K Bauwens; J Sehouli; F Porzsolt; G Rademacher; S Mutze; A Ekkernkamp
Journal:  Br J Surg       Date:  2001-07       Impact factor: 6.939

Review 3.  Intra-abdominal solid organ injury in children: diagnosis and treatment.

Authors:  Barbara A Gaines
Journal:  J Trauma       Date:  2009-08

4.  Complications of nonoperative management of pediatric blunt hepatic injury: Diagnosis, management, and outcomes.

Authors:  Steven R Giss; Nick Dobrilovic; Rebeccah L Brown; Victor F Garcia
Journal:  J Trauma       Date:  2006-08

5.  Injuries associated with pediatric liver trauma.

Authors:  John A Deluca; Damian R Maxwell; Sarah K Flaherty; Jason M Prigozen; Mary E Scragg; Patrick A Stone
Journal:  Am Surg       Date:  2007-01       Impact factor: 0.688

6.  A multicenter study of the risk of intra-abdominal injury in children after normal abdominal computed tomography scan results in the emergency department.

Authors:  Benjamin T Kerrey; Alexander J Rogers; Lois K Lee; Kathleen Adelgais; Michael Tunik; Stephen M Blumberg; Kimberly S Quayle; Peter E Sokolove; David H Wisner; Michelle L Miskin; Nathan Kuppermann; James F Holmes
Journal:  Ann Emerg Med       Date:  2013-04-26       Impact factor: 5.721

7.  The role of elevated liver transaminase levels in children with blunt abdominal trauma.

Authors:  Dolunay Karaduman; Akile Sarioglu-Buke; Ilknur Kilic; Ercan Gurses
Journal:  Injury       Date:  2003-05       Impact factor: 2.586

8.  Identification of children with intra-abdominal injuries after blunt trauma.

Authors:  James F Holmes; Peter E Sokolove; William E Brant; Michael J Palchak; Cheryl W Vance; John T Owings; Nathan Kuppermann
Journal:  Ann Emerg Med       Date:  2002-05       Impact factor: 5.721

9.  Is computed tomography a useful adjunct to the clinical examination for the diagnosis of pediatric gastrointestinal perforation from blunt abdominal trauma in children?

Authors:  C T Albanese; M P Meza; M J Gardner; S D Smith; M I Rowe; J M Lynch
Journal:  J Trauma       Date:  1996-03

10.  Blunt abdominal trauma in children: how predictive is ALT for liver injury?

Authors:  C A Bevan; C S Palmer; J R Sutcliffe; P Rao; S Gibikote; J Crameri
Journal:  Emerg Med J       Date:  2009-04       Impact factor: 2.740

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  1 in total

1.  Posttraumatic levels of liver enzymes can reduce the need for CT in children: a retrospective cohort study.

Authors:  Peter James Bruhn; Lene Østerballe; Jens Hillingsø; Lars Bo Svendsen; Frederik Helgstrand
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2016-08-25       Impact factor: 2.953

  1 in total

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