Literature DB >> 26812011

A Wacky Bridge to mTORC1 Dimerization.

Jacques Montagne1.   

Abstract

The activity of the mTORC1 protein complex depends on multiple metabolic inputs that regulate dimerization, recruitment to the lysosome, and activation. In this issue of Developmental Cell, David-Morrison et al. (2016) show that the Drosophila protein Wacky and its mammalian counterpart WAC act as adaptors in the process of mTORC1 dimerization.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID: 26812011     DOI: 10.1016/j.devcel.2016.01.006

Source DB:  PubMed          Journal:  Dev Cell        ISSN: 1534-5807            Impact factor:   12.270


  2 in total

1.  Differential metabolic sensitivity of insulin-like-response- and TORC1-dependent overgrowth in Drosophila fat cells.

Authors:  Maelle Devilliers; Damien Garrido; Mickael Poidevin; Thomas Rubin; Arnaud Le Rouzic; Jacques Montagne
Journal:  Genetics       Date:  2021-03-03       Impact factor: 4.562

2.  Short and long sleeping mutants reveal links between sleep and macroautophagy.

Authors:  Joseph L Bedont; Hirofumi Toda; Mi Shi; Christine H Park; Christine Quake; Carly Stein; Anna Kolesnik; Amita Sehgal
Journal:  Elife       Date:  2021-06-04       Impact factor: 8.140

  2 in total

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