| Literature DB >> 26812011 |
Abstract
The activity of the mTORC1 protein complex depends on multiple metabolic inputs that regulate dimerization, recruitment to the lysosome, and activation. In this issue of Developmental Cell, David-Morrison et al. (2016) show that the Drosophila protein Wacky and its mammalian counterpart WAC act as adaptors in the process of mTORC1 dimerization.Entities:
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Year: 2016 PMID: 26812011 DOI: 10.1016/j.devcel.2016.01.006
Source DB: PubMed Journal: Dev Cell ISSN: 1534-5807 Impact factor: 12.270