Literature DB >> 26811640

Inflammatory bowel disease associated neoplasia: A surgeon's perspective.

Azah A Althumairi1, Mark G Lazarev1, Susan L Gearhart1.   

Abstract

Inflammatory bowel disease (IBD) is associated with increased risk of colorectal cancer (CRC). The risk is known to increase with longer duration of the disease, family history of CRC, and history of primary sclerosing cholangitis. The diagnosis of the neoplastic changes associated with IBD is difficult owing to the heterogeneous endoscopic appearance and inter-observer variability of the pathological diagnosis. Screening and surveillance guidelines have been established which aim for early detection of neoplasia. Several surgical options are available for the treatment of IBD-associated neoplasia. Patients' morbidities, risk factors for CRC, degree and the extent of neoplasia must be considered in choosing the surgical treatment. A multidisciplinary team including the surgeon, gastroenterologist, pathologist, and the patient who has a clear understanding of the nature of their disease is needed to optimize outcomes.

Entities:  

Keywords:  Colectomy; Colorectal cancer; Dysplasia; Endoscopy; Inflammatory bowel disease; Surveillance

Mesh:

Substances:

Year:  2016        PMID: 26811640      PMCID: PMC4716048          DOI: 10.3748/wjg.v22.i3.961

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  105 in total

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Review 3.  Colorectal cancer in inflammatory bowel disease: review of the evidence.

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Review 7.  Microbes as Master Immunomodulators: Immunopathology, Cancer and Personalized Immunotherapies.

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  7 in total

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