| Literature DB >> 26809453 |
E Şahan1, S Şahan2, M Karamanlıoğlu3, M Gul4, O Tufekcioğlu2.
Abstract
Cardiomyopathy is a disease of the heart muscle resulting from genetic defects, cardiac myocyte injury, or infiltration of the myocardium. Cardiomyopathies are traditionally defined as dilated, restrictive, and hypertrophic cardiomyopathy. Today, the genetic basis of most diseases has been clearly defined and has influenced the approach to familial diseases such as cardiomyopathies. Traditional definitions of cardiomyopathies, such as those by the American Heart Association and the European Society of Cardiology, do not consider the genetic basis of cardiomyopathies. In 2013, the World Heart Federation added the genetic basis of cardiomyopathies and proposed a descriptive genotype-phenotype nosology system termed "MOGE(S)." The MOGE(S) system resembles the TNM classification system for malignancy, and therefore it can be useful for the diagnosis, management, and treatment of cardiomyopathies in a similar manner to cancer management.Entities:
Keywords: Cardiomyopathy; Classification; Genetics; MOGES; Myocardium
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Year: 2016 PMID: 26809453 DOI: 10.1007/s00059-015-4394-0
Source DB: PubMed Journal: Herz ISSN: 0340-9937 Impact factor: 1.443