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Literature DB >> 26806652

Click-Crosslinked Injectable Gelatin Hydrogels.

Sandeep T Koshy^1,2,3, Rajiv M Desai^1,2, Pascal Joly^1,4, Jianyu Li^1,2, Rishi K Bagrodia^1,2, Sarah A Lewin¹, Neel S Joshi^1,2, David J Mooney^1,2.

Abstract

Injectable gelatin hydrogels formed with bioorthogonal click chemistry (ClickGel) are cell-responsive ECM mimics for in vitro and in vivo biomaterials applications. Gelatin polymers with pendant norbornene (GelN) or tetrazine (GelT) groups can quickly and spontaneously crosslink upon mixing, allowing for high viability of encapsulated cells, establishment of 3D elongated cell morphologies, and biodegradation when injected in vivo.

Entities: CellLine Chemical Disease Gene Species

Keywords: click chemistry; degradable; gelatin; hydrogels; injectable

Mesh：

Substances：

Year: 2016 PMID： 26806652 PMCID： PMC4849477 DOI： 10.1002/adhm.201500757

Source DB: PubMed Journal: Adv Healthc Mater ISSN： 2192-2640 Impact factor: 9.933

23 in total

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Journal: Tissue Eng Part A Date: 2009-11 Impact factor: 3.845

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Authors: Elke Kaemmerer; Ferry P W Melchels; Boris M Holzapfel; Tobias Meckel; Dietmar W Hutmacher; Daniela Loessner
Journal: Acta Biomater Date: 2014-02-28 Impact factor: 8.947

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2. Designing hydrogels for controlled drug delivery.

Authors: Jianyu Li; David J Mooney
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3. Hybrid hydrogels for biomedical applications.

Authors: Luisa L Palmese; Raj Kumar Thapa; Millicent O Sullivan; Kristi L Kiick
Journal: Curr Opin Chem Eng Date: 2019-06-04 Impact factor: 5.163

Review 4. Recent Progress in Developing Injectable Matrices for Enhancing Cell Delivery and Tissue Regeneration.

Authors: Xinming Tong; Fan Yang
Journal: Adv Healthc Mater Date: 2017-12-27 Impact factor: 9.933

5. Progress in Vocal Fold Regenerative Biomaterials: An Immunological Perspective.

Authors: Patrick T Coburn; Xuan Li; Jianyu Y Li; Yo Kishimoto; Nicole Y K Li-Jessen
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6. Fabrication Parameter-Dependent Physico-Chemical Properties of Thiolated Gelatin/PEGDA Interpenetrating Network Hydrogels.

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