| Literature DB >> 2680616 |
Abstract
Ovarian follicles of a preovulatory size were encouraged to develop by extending the pill-free period of combine, triphasic oral contraceptive (OC) cycles. Despite recommencement of OC therapy, most follicles continued to grow and then respond to gonadotropin administration by both rupture and luteinization. It is concluded that follicles developing during OC cycles have the potential for ovulation, but this is of doubtful clinical significance for the vast majority of women.Entities:
Keywords: Biology; Clinical Research; Contraception; Contraceptive Agents; Contraceptive Agents, Estrogen; Contraceptive Agents, Female; Contraceptive Agents, Progestin; Contraceptive Methods; Contraceptive Mode Of Action; Developed Countries; Endocrine System; Ethinyl Estradiol; Europe; Family Planning; Gonadotropins; Gonadotropins, Chorionic; Hormones; Human Volunteers; Levonorgestrel; Northern Europe; Oral Contraceptives; Oral Contraceptives, Combined; Oral Contraceptives, Phasic; Ovulation Suppression; Physiology; Research Methodology; United Kingdom
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Year: 1989 PMID： 2680616 DOI： 10.1016/s0015-0282(16)60967-6
Source DB: PubMed Journal: Fertil Steril ISSN： 0015-0282 Impact factor: 7.329