Maura M Zylla1, Johannes Brachmann2, Thorsten Lewalter3, Ellen Hoffmann4, Karl-Heinz Kuck5, Dietrich Andresen6, Stephan Willems7, Matthias Hochadel8, Jochen Senges8, Hugo A Katus1, Dierk Thomas9. 1. Department of Cardiology, Medical University Hospital, Im Neuenheimer Feld 410, Heidelberg, Germany. 2. Department of Cardiology, Hospital Coburg, Ketschendorfer Str. 33, Coburg, Germany. 3. Isar Heart Center Munich, Sonnenstraße 24-26, Munich, Germany. 4. Department of Cardiology/Intensive Care Medicine, Heart Center Munich-Bogenhausen, Englschalkinger Str. 77, Munich, Germany. 5. Department of Cardiology, Asklepios Hospital St. Georg, Lohmühlenstraße 5, Hamburg, Germany. 6. Department of Cardiology, Vivantes Hospital, Klinikum am Urban, Dieffenbachstraße 1, Berlin, Germany. 7. University Heart Center, Department of Cardiology/Electrophysiology, Martinistraße 52, Hamburg, Germany. 8. Stiftung Institut für Herzinfarktforschung, IHF, Bremserstraße 79, Ludwigshafen, Germany. 9. Department of Cardiology, Medical University Hospital, Im Neuenheimer Feld 410, Heidelberg, Germany. Electronic address: dierk.thomas@med.uni-heidelberg.de.
Abstract
AIMS: This investigation addresses procedural characteristics of catheter ablation in patients with atrial fibrillation (AF) and sinus bradycardia. METHODS: From the prospective, multi-center German Ablation Registry 1073 patients with sinus rhythm at the time of AF ablation were divided into two groups according to heart rate at start of procedure (A, <60 beats per minute (bpm), n=197; B, 60-99bpm, n=876). RESULTS: Acute procedural success was high (≥98%) and similar between groups. Procedure duration and energy application time were increased in group A (180min vs. 155min and 2561s vs. 1879s, respectively). Major complications were more frequent in group A (2.2% vs. 0.5%), and a greater proportion of these patients was discharged under antiarrhythmic medication (64% vs. 52%). CONCLUSION: Catheter ablation of AF with concomitant sinus bradycardia is associated with high procedural efficacy, longer procedure- and energy application durations, and a slightly elevated complication rate.
AIMS: This investigation addresses procedural characteristics of catheter ablation in patients with atrial fibrillation (AF) and sinus bradycardia. METHODS: From the prospective, multi-center German Ablation Registry 1073 patients with sinus rhythm at the time of AF ablation were divided into two groups according to heart rate at start of procedure (A, <60 beats per minute (bpm), n=197; B, 60-99bpm, n=876). RESULTS: Acute procedural success was high (≥98%) and similar between groups. Procedure duration and energy application time were increased in group A (180min vs. 155min and 2561s vs. 1879s, respectively). Major complications were more frequent in group A (2.2% vs. 0.5%), and a greater proportion of these patients was discharged under antiarrhythmic medication (64% vs. 52%). CONCLUSION: Catheter ablation of AF with concomitant sinus bradycardia is associated with high procedural efficacy, longer procedure- and energy application durations, and a slightly elevated complication rate.
Authors: Lara Wagner; Fabrice F Darche; Dierk Thomas; Patrick Lugenbiel; Panagiotis Xynogalos; Svenja Seide; Eberhard P Scholz; Hugo A Katus; Patrick A Schweizer Journal: Clin Res Cardiol Date: 2020-05-13 Impact factor: 5.460