Literature DB >> 26801870

Prolonged duration of untreated psychosis: a problem that needs addressing.

Jack Cotter1, Elisabeth Zabel2, Paul French2,3, Alison R Yung1,2.   

Abstract

AIM: The duration of untreated psychosis (DUP) refers to the period of time between the emergence of psychotic symptoms and the initiation of appropriate clinical treatment. Prolonged DUP is associated with a range of adverse consequences, including more severe illness course, cognitive deficits and poor functioning. Problems with recognition of illness and in seeking help contribute to DUP, but another major cause of prolonged DUP is delays within secondary mental health services. In an attempt to reduce these delays, National Health Service England and the Department of Health have set new targets to improve access to early intervention services which will come into effect in April 2016. Given this background, we aimed to examine the DUP and pathways to care of new patients entering an early intervention service. We also examined whether they were receiving National Institute for Health and Care Excellence (NICE) concordant treatment. This will enable us to establish a baseline so that the impact of the new targets can be determined and to assess the degree of change that will be required to implement these.
METHODS: De-identified electronic records of 165 patients accepted into the service over a 12-month period were analysed.
RESULTS: Median DUP was 6 months. There was a median of 2 contacts prior to service entry. Community Mental Health Teams were the largest source of referrals.
CONCLUSIONS: The majority of patients had a DUP exceeding the international target of 3 months. The findings appear to support previous evidence that this may be partially attributable to significant delays within the mental health care system.
© 2016 John Wiley & Sons Australia, Ltd.

Entities:  

Keywords:  duration of untreated psychosis; early intervention; pathways to care; psychosis

Mesh:

Year:  2016        PMID: 26801870     DOI: 10.1111/eip.12308

Source DB:  PubMed          Journal:  Early Interv Psychiatry        ISSN: 1751-7885            Impact factor:   2.732


  6 in total

1.  Clinical and demographic correlates of stigma in first-episode psychosis: the impact of duration of untreated psychosis.

Authors:  K T Mueser; N R DeTore; M A Kredlow; M L Bourgeois; D L Penn; K Hintz
Journal:  Acta Psychiatr Scand       Date:  2019-10-11       Impact factor: 6.392

2.  Relationship between Duration of Untreated Psychosis and Intrinsic Corticostriatal Connectivity in Patients with Early Phase Schizophrenia.

Authors:  Deepak K Sarpal; Delbert G Robinson; Christina Fales; Todd Lencz; Miklos Argyelan; Katherine H Karlsgodt; Juan A Gallego; Majnu John; John M Kane; Philip R Szeszko; Anil K Malhotra
Journal:  Neuropsychopharmacology       Date:  2017-03-15       Impact factor: 7.853

3.  Early Intervention in Psychosis in Young People: A Population and Public Health Perspective.

Authors:  Ashok Malla; Patrick McGorry
Journal:  Am J Public Health       Date:  2019-06       Impact factor: 9.308

4.  Transforming the Treatment of Schizophrenia in the United States: The RAISE Initiative.

Authors:  Lisa B Dixon; Howard H Goldman; Vinod H Srihari; John M Kane
Journal:  Annu Rev Clin Psychol       Date:  2018-01-12       Impact factor: 18.561

Review 5.  Telemental Health and the Management of Psychosis.

Authors:  Amy L Donahue; Jennifer Rodriguez; Jay H Shore
Journal:  Curr Psychiatry Rep       Date:  2021-03-24       Impact factor: 5.285

6.  Effects of socio-demographic characteristics, premorbid functioning, and insight on duration of untreated psychosis in first-episode schizophrenia or schizophreniform disorder in Northern Malawi.

Authors:  Atipatsa C Kaminga; Wenjie Dai; Aizhong Liu; Japhet Myaba; Richard Banda; Shi W Wen
Journal:  Early Interv Psychiatry       Date:  2019-02-01       Impact factor: 2.732

  6 in total

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