Literature DB >> 26801226

A 'test and treat' prevention strategy in Australia requires innovative HIV testing models: a cohort study of repeat testing among 'high-risk' men who have sex with men.

Anna L Wilkinson1, Carol El-Hayek2, Tim Spelman2, Christopher K Fairley3, David Leslie4, Emma S McBryde5, Margaret Hellard6, Mark Stoové1.   

Abstract

OBJECTIVES: HIV diagnoses among men who have sex with men (MSM) in several high-income countries, including Australia, have increased substantially over recent years. Australia, in line with global prevention strategies, has emphasised a 'test and treat' HIV prevention strategy which relies on timely detection of HIV through frequent testing by those at risk. We examined trends in repeat testing among MSM defined as 'high-risk' according to Australian testing guidelines.
METHODS: HIV test records from MSM attending high caseload clinics in Melbourne 2007-2013 and classified as high-risk were analysed. Binary outcomes of 'test within 3 months' and 'test within 6 months' were assigned to tests within individuals' panel of records. Negative binomial regressions assessed trends in overall HIV testing and returning within 3 and 6 months. Annualised proportions of return tests (2007-2012) were compared using two-sample z tests.
RESULTS: Across 18 538 tests among 7117 high-risk MSM attending primary care clinics in Melbourne (2007-2013), the number of annual HIV tests increased (p<0.01). Between 2007 and 2012 annualised proportions of tests with a subsequent test within 3 and 6 months also increased (p<0.01); however, by 2012 only 36.4% and 15.1% of tests were followed by another test inside 6 and 3 months, respectively.
CONCLUSIONS: Repeat testing among high-risk MSM in Australia remains unacceptably low, with recent modest increases in testing unlikely to deliver meaningful prevention impact. Removing known barriers to HIV testing is needed to maximise the potential benefit of test and treat-based HIV prevention. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Entities:  

Keywords:  HIV TESTING; MEN; PREVENTION; SEXUAL BEHAVIOUR

Mesh:

Year:  2016        PMID: 26801226     DOI: 10.1136/sextrans-2015-052421

Source DB:  PubMed          Journal:  Sex Transm Infect        ISSN: 1368-4973            Impact factor:   3.519


  10 in total

1.  Acceptability and HIV Prevention Benefits of a Peer-Based Model of Rapid Point of Care HIV Testing for Australian Gay, Bisexual and Other Men Who Have Sex with Men.

Authors:  David Leitinger; Kathleen E Ryan; Graham Brown; Alisa Pedrana; Anna L Wilkinson; Claire Ryan; Margaret Hellard; Mark Stoové
Journal:  AIDS Behav       Date:  2018-01

2.  A Systems Thinking Approach to Understanding and Demonstrating the Role of Peer-Led Programs and Leadership in the Response to HIV and Hepatitis C: Findings From the W3 Project.

Authors:  Graham Brown; Daniel Reeders; Aaron Cogle; Annie Madden; Jules Kim; Darryl O'Donnell
Journal:  Front Public Health       Date:  2018-08-31

3.  Motivations and Barriers to Routine HIV Testing Among Men Who Have Sex with Men in New York City.

Authors:  Paul Kobrak; Robert H Remien; Julie E Myers; Paul Salcuni; Zoe Edelstein; Benjamin Tsoi; Theodorus Sandfort
Journal:  AIDS Behav       Date:  2022-05-10

4.  Usability of dual HIV/syphilis self-testing among men who have sex with men in China: study protocol for a three-arm randomised controlled trial.

Authors:  Hong Zhang; Min Wang; Yun Zhang; Ping Cen; Chuanyi Ning; Sumin Tan; Haimei Huang; Jiawen Zhu; Weiyi Tian; Jinli Mo; Jieling Mo
Journal:  BMJ Open       Date:  2022-10-10       Impact factor: 3.006

5.  Undiagnosed HIV infections among gay and bisexual men increasingly contribute to new infections in Australia.

Authors:  Richard T Gray; David P Wilson; Rebecca J Guy; Mark Stoové; Margaret E Hellard; Garrett P Prestage; Toby Lea; John de Wit; Martin Holt
Journal:  J Int AIDS Soc       Date:  2018-04       Impact factor: 5.396

6.  Protocol for an HIV Pre-exposure Prophylaxis (PrEP) Population Level Intervention Study in Victoria Australia: The PrEPX Study.

Authors:  Kathleen E Ryan; Anne Mak; Mark Stoove; Brian Price; Christopher K Fairley; Simon Ruth; Luxshimi Lal; Jason Asselin; Carol El-Hayek; Long Nguyen; Colin Batrouney; David Wilson; John Lockwood; Dean Murphy; Vincent J Cornelisse; Norman Roth; Jeff Willcox; Christina C Chang; Judy Armishaw; Ban K Tee; Matthew Penn; George Forgan-Smith; Christopher Williams; Jeff Montgomery; Kat Byron; Alison Coelho; Brent Allen; Jeremy Wiggins; Jenny Kelsall; Olga Vujovic; Michael West; Anna B Pierce; Daniel Gallant; Charlotte Bell; John B F de Wit; Jennifer F Hoy; Steve L Wesselingh; Robert M Grant; Edwina J Wright
Journal:  Front Public Health       Date:  2018-05-29

7.  Trial and error: evaluating and refining a community model of HIV testing in Australia.

Authors:  Kathleen E Ryan; Alisa Pedrana; David Leitinger; Anna L Wilkinson; Peter Locke; Margaret E Hellard; Mark Stoové
Journal:  BMC Health Serv Res       Date:  2017-10-10       Impact factor: 2.655

8.  Assessment of service refinement and its impact on repeat HIV testing by client's access to Australia's universal healthcare system: a retrospective cohort study.

Authors:  Kathleen E Ryan; Anna L Wilkinson; Jason Asselin; David P Leitinger; Peter Locke; Alisa Pedrana; Margaret Hellard; Mark Stoové
Journal:  J Int AIDS Soc       Date:  2019-08       Impact factor: 5.396

9.  Risk of Subsequent HIV Infection Following Sexually Transmissible Infections Among Men Who Have Sex With Men.

Authors:  Brendan L Harney; Paul A Agius; Carol El-Hayek; Christopher K Fairley; Eric P F Chow; Norman Roth; B K Tee; David Leslie; Gilda Tachedjian; Margaret Hellard; Mark Stoové
Journal:  Open Forum Infect Dis       Date:  2019-08-23       Impact factor: 3.835

10.  Trends in late and advanced HIV diagnoses among migrants in Australia; implications for progress on Fast-Track targets: A retrospective observational study.

Authors:  Tafireyi Marukutira; Praveena Gunaratnam; Caitlin Douglass; Muhammad S Jamil; Skye McGregor; Rebecca Guy; Richard Thomas Gray; Tim Spelman; Danielle Horyniak; Nasra Higgins; Carolien Giele; Suzanne Mary Crowe; Mark Stoove; Margaret Hellard
Journal:  Medicine (Baltimore)       Date:  2020-02       Impact factor: 1.817

  10 in total

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