Hee Kyung Kim1, Paul Horn2, Bernard J Dardzinski3, Dong Hoon Kim4, Tal Laor1. 1. Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA. 2. Department of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA. 3. Department of Radiology, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA 19104, USA. 4. Department of Pharmacology, Korea University College of Medicine, Seoul 02841, Korea.
Abstract
OBJECTIVE: Our aim was to evaluate the cartilage cap of osteochondromas using T2 maps and to compare these values to those of normal patellar cartilage, from age and gender matched controls. MATERIALS AND METHODS: This study was approved by the Institutional Review Board and request for informed consent was waived. Eleven children (ages 5-17 years) with osteochondromas underwent MR imaging, which included T2-weighted fat suppressed and T2 relaxation time mapping (echo time = 9-99/repetition time = 1500 msec) sequences. Lesion origins were femur (n = 5), tibia (n = 3), fibula (n = 2), and scapula (n = 1). Signal intensity of the cartilage cap, thickness, mean T2 relaxation times, and T2 spatial variation (mean T2 relaxation times as a function of distance) were evaluated. Findings were compared to those of patellar cartilage from a group of age and gender matched subjects. RESULTS: The cartilage caps showed a fluid-like high T2 signal, with mean thickness of 4.8 mm. The mean value of mean T2 relaxation times of the osteochondromas was 264.0 ± 80.4 msec (range, 151.0-366.0 msec). Mean T2 relaxation times were significantly longer than the values from patellar cartilage (39.0 msec) (p < 0.0001). These findings were observed with T2 spatial variation plots across the entire distance of the cartilage cap, with the most pronounced difference in the middle section of the cartilage. CONCLUSION: Longer T2 relaxation times of the cartilage caps of osteochondromas should be considered as normal, and likely to reflect an increased water content, different microstructure and component.
OBJECTIVE: Our aim was to evaluate the cartilage cap of osteochondromas using T2 maps and to compare these values to those of normal patellar cartilage, from age and gender matched controls. MATERIALS AND METHODS: This study was approved by the Institutional Review Board and request for informed consent was waived. Eleven children (ages 5-17 years) with osteochondromas underwent MR imaging, which included T2-weighted fat suppressed and T2 relaxation time mapping (echo time = 9-99/repetition time = 1500 msec) sequences. Lesion origins were femur (n = 5), tibia (n = 3), fibula (n = 2), and scapula (n = 1). Signal intensity of the cartilage cap, thickness, mean T2 relaxation times, and T2 spatial variation (mean T2 relaxation times as a function of distance) were evaluated. Findings were compared to those of patellar cartilage from a group of age and gender matched subjects. RESULTS: The cartilage caps showed a fluid-like high T2 signal, with mean thickness of 4.8 mm. The mean value of mean T2 relaxation times of the osteochondromas was 264.0 ± 80.4 msec (range, 151.0-366.0 msec). Mean T2 relaxation times were significantly longer than the values from patellar cartilage (39.0 msec) (p < 0.0001). These findings were observed with T2 spatial variation plots across the entire distance of the cartilage cap, with the most pronounced difference in the middle section of the cartilage. CONCLUSION: Longer T2 relaxation times of the cartilage caps of osteochondromas should be considered as normal, and likely to reflect an increased water content, different microstructure and component.
Entities:
Keywords:
Cartilage cap; Osteochondroma; T2 relaxation time mapping
Authors: K Huch; V Mordstein; J Stöve; A G Nerlich; H Amholdt; G Delling; W Puhl; K P Günther; R E Brenner Journal: Eur J Histochem Date: 2002 Impact factor: 3.188
Authors: Carlos E de Andrea; Malgorzata Wiweger; Frans Prins; Judith V M G Bovée; Salvatore Romeo; Pancras C W Hogendoorn Journal: Lab Invest Date: 2010-04-26 Impact factor: 5.662
Authors: Hee Kyung Kim; Tal Laor; Thomas B Graham; Christopher G Anton; Shelia R Salisbury; Judy M Racadio; Bernard J Dardzinski Journal: AJR Am J Roentgenol Date: 2010-10 Impact factor: 3.959
Authors: Hee Kyung Kim; Sahar Shiraj; Christopher G Anton; Paul S Horn; Bernard J Dardzinski Journal: AJR Am J Roentgenol Date: 2014-03 Impact factor: 3.959
Authors: Panagiotis Kitsoulis; Vassiliki Galani; Kalliopi Stefanaki; Georgios Paraskevas; Georgios Karatzias; Niki John Agnantis; Maria Bai Journal: In Vivo Date: 2008 Sep-Oct Impact factor: 2.155
Authors: Bernard J Dardzinski; Tal Laor; Vincent J Schmithorst; Lance Klosterman; T Brent Graham Journal: Radiology Date: 2002-10 Impact factor: 11.105