Literature DB >> 26797932

A Case Report of a Carbamazepine Overdose With Focus on Pharmacokinetic Aspects.

N Mittag1, S Meister2, A M J Berg1, U I Walther1.   

Abstract

In this article a case of carbamazepine overdose is reported. It is common to use immuno-based methods in the field of therapeutic drug monitoring but it might be difficult to adapt such values to toxicological cases. For carbamazepine overdoses it is recommended also to determine the metabolite carbamazepine-10,11-epoxide. Especially for critical conditions a definite substance identification should be performed. In addition, quantifying main metabolites is recommended for an acute clinical toxicological assessment. © Georg Thieme Verlag KG Stuttgart · New York.

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Year:  2016        PMID: 26797932     DOI: 10.1055/s-0035-1569268

Source DB:  PubMed          Journal:  Pharmacopsychiatry        ISSN: 0176-3679            Impact factor:   5.788


  2 in total

1.  Protective effect of vitamin C on chronic carbamazepine-induced reproductive toxicity in male wistar rats.

Authors:  Ganiu Jimoh Akorede
Journal:  Toxicol Rep       Date:  2020-01-27

Review 2.  Pharmacogenetics of Carbamazepine and Valproate: Focus on Polymorphisms of Drug Metabolizing Enzymes and Transporters.

Authors:  Teresa Iannaccone; Carmine Sellitto; Valentina Manzo; Francesca Colucci; Valentina Giudice; Berenice Stefanelli; Antonio Iuliano; Giulio Corrivetti; Amelia Filippelli
Journal:  Pharmaceuticals (Basel)       Date:  2021-03-01
  2 in total

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