Ryoma Michishita1,2, Takuro Matsuda3,4, Shotaro Kawakami3,5, Akira Kiyonaga3,5, Hiroaki Tanaka3,5, Natsumi Morito6,7, Yasuki Higaki3,5. 1. Department of Health Development, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8555, Japan. rmichishita@med.uoeh-u.ac.jp. 2. The Fukuoka University Institute for Physical Activity, Fukuoka, Japan. rmichishita@med.uoeh-u.ac.jp. 3. The Fukuoka University Institute for Physical Activity, Fukuoka, Japan. 4. Department of Rehabilitation, Fukuoka University Hospital, Fukuoka, Japan. 5. Laboratory of Exercise Physiology, Faculty of Health and Sports Science, Fukuoka University, Fukuoka, Japan. 6. Fukuoka University Health Care Center, Fukuoka, Japan. 7. Department of Cardiology, Fukuoka University School of Medicine, Fukuoka, Japan.
Abstract
AIM: This study was retrospectively designed to evaluate the influence of healthy lifestyle behaviors on the incidence of chronic kidney disease (CKD) during a 5-year follow-up period in middle-aged and older males. METHODS: The subjects included 252 males without a history of cardiovascular disease, stroke, renal dysfunction and/or dialysis treatment who were not taking any medications. Their lifestyle behaviors were evaluated using a standardized self-administered questionnaire and defined as follows: (1) habitual moderate exercise, (2) daily physical activity, (3) fast walking speed, (4) slow eating speed, (5) no late-night dinner, (6) no bedtime snacking and (7) no skipping breakfast. The participants were divided into four categories, which were classified into quartile distributions according to the number of healthy lifestyle behaviors (7-6, 5, 4 and ≤3 groups). RESULTS: After 5 years, the incidence of CKD [estimated glomerular filtration rate (eGFR) <60 ml/min/1.73 m(2) and/or proteinuria] was observed in 23 subjects (9.1%). The Kaplan-Meier survival curves showed that the cumulative incidence of CKD significantly decreased according to an increase in the number of healthy lifestyle behaviors (log-rank test: p = 0.003). According to a multivariate analysis, habitual moderate exercise [hazard ratio (HR) 0.20, 95% confidence of interval (CI) 0.06-0.69, p = 0.011] and no bedtime snacking (HR 0.19, 95 % CI 0.08-0.48, p = 0.004) were significantly associated with the incidence of CKD. CONCLUSIONS: These results suggest that the accumulation of healthy lifestyle behaviors, especially those related to habitual moderate exercise and no bedtime snacking, is considered to be important to reduce the risk of CKD.
AIM: This study was retrospectively designed to evaluate the influence of healthy lifestyle behaviors on the incidence of chronic kidney disease (CKD) during a 5-year follow-up period in middle-aged and older males. METHODS: The subjects included 252 males without a history of cardiovascular disease, stroke, renal dysfunction and/or dialysis treatment who were not taking any medications. Their lifestyle behaviors were evaluated using a standardized self-administered questionnaire and defined as follows: (1) habitual moderate exercise, (2) daily physical activity, (3) fast walking speed, (4) slow eating speed, (5) no late-night dinner, (6) no bedtime snacking and (7) no skipping breakfast. The participants were divided into four categories, which were classified into quartile distributions according to the number of healthy lifestyle behaviors (7-6, 5, 4 and ≤3 groups). RESULTS: After 5 years, the incidence of CKD [estimated glomerular filtration rate (eGFR) <60 ml/min/1.73 m(2) and/or proteinuria] was observed in 23 subjects (9.1%). The Kaplan-Meier survival curves showed that the cumulative incidence of CKD significantly decreased according to an increase in the number of healthy lifestyle behaviors (log-rank test: p = 0.003). According to a multivariate analysis, habitual moderate exercise [hazard ratio (HR) 0.20, 95% confidence of interval (CI) 0.06-0.69, p = 0.011] and no bedtime snacking (HR 0.19, 95 % CI 0.08-0.48, p = 0.004) were significantly associated with the incidence of CKD. CONCLUSIONS: These results suggest that the accumulation of healthy lifestyle behaviors, especially those related to habitual moderate exercise and no bedtime snacking, is considered to be important to reduce the risk of CKD.
Authors: Cassianne Robinson-Cohen; Alyson J Littman; Glen E Duncan; Noel S Weiss; Michael C Sachs; John Ruzinski; John Kundzins; Denise Rock; Ian H de Boer; T Alp Ikizler; Jonathan Himmelfarb; Bryan R Kestenbaum Journal: J Am Soc Nephrol Date: 2013-12-12 Impact factor: 10.121
Authors: G L Bakris; M Williams; L Dworkin; W J Elliott; M Epstein; R Toto; K Tuttle; J Douglas; W Hsueh; J Sowers Journal: Am J Kidney Dis Date: 2000-09 Impact factor: 8.860
Authors: Michael F Leitzmann; Yikyung Park; Aaron Blair; Rachel Ballard-Barbash; Traci Mouw; Albert R Hollenbeck; Arthur Schatzkin Journal: Arch Intern Med Date: 2007-12-10