Literature DB >> 26796362

Use of hematopoietic cell transplants to achieve tolerance in patients with solid organ transplants.

Samuel Strober1.   

Abstract

The goals of tolerance in patients with solid organ transplants are to eliminate the lifelong need for immunosuppressive (IS) drugs and to prevent graft loss due to rejection or drug toxicity. Tolerance with complete withdrawal of IS drugs has been achieved in recipients of HLA-matched and mismatched living donor kidney transplants in 3 medical centers using hematopoietic cell transplants to establish mixed or complete chimerism.
© 2016 by The American Society of Hematology.

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Year:  2016        PMID： 26796362      PMCID： PMC4807420          DOI： 10.1182/blood-2015-12-685107

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  66 in total

1.  Actively acquired tolerance of foreign cells.

Authors:  R E BILLINGHAM; L BRENT; P B MEDAWAR
Journal:  Nature       Date:  1953-10-03       Impact factor: 49.962

2.  Long-term prevention of chronic allograft rejection by regulatory T-cell immunotherapy involves host Foxp3-expressing T cells.

Authors:  Lise Pasquet; Jean-Yves Douet; Tim Sparwasser; Paola Romagnoli; Joost P M van Meerwijk
Journal:  Blood       Date:  2013-04-11       Impact factor: 22.113

Review 3.  Intrathymic and extrathymic tolerance in bone marrow chimeras.

Authors:  J Sprent; H Kosaka; E K Gao; C D Surh; S R Webb
Journal:  Immunol Rev       Date:  1993-06       Impact factor: 12.988

4.  Protective conditioning for acute graft-versus-host disease.

Authors:  Robert Lowsky; Tsuyoshi Takahashi; Yin Ping Liu; Sussan Dejbakhsh-Jones; F Carl Grumet; Judith A Shizuru; Ginna G Laport; Keith E Stockerl-Goldstein; Laura J Johnston; Richard T Hoppe; Daniel A Bloch; Karl G Blume; Robert S Negrin; Samuel Strober
Journal:  N Engl J Med       Date:  2005-09-29       Impact factor: 91.245

5.  Long-term follow-up of recipients of combined human leukocyte antigen-matched bone marrow and kidney transplantation for multiple myeloma with end-stage renal disease.

Authors:  Thomas R Spitzer; Megan Sykes; Nina Tolkoff-Rubin; Tatsuo Kawai; Steven L McAfee; Bimalangshu R Dey; Karen Ballen; Francis Delmonico; Susan Saidman; David H Sachs; A Benedict Cosimi
Journal:  Transplantation       Date:  2011-03-27       Impact factor: 4.939

6.  Induced immune tolerance for kidney transplantation.

Authors:  John D Scandling; Stephan Busque; Judith A Shizuru; Edgar G Engleman; Samuel Strober
Journal:  N Engl J Med       Date:  2011-10-06       Impact factor: 91.245

7.  Mixed chimerism and tolerance without whole body irradiation in a large animal model.

Authors:  Y Fuchimoto; C A Huang; K Yamada; A Shimizu; H Kitamura; R B Colvin; V Ferrara; M C Murphy; M Sykes; M White-Scharf; D M Neville; D H Sachs
Journal:  J Clin Invest       Date:  2000-06       Impact factor: 14.808

8.  Survival of primates following orthotopic cardiac transplantation treated with total lymphoid irradiation and chemical immune suppression.

Authors:  J L Pennock; B A Reitz; C P Bieber; S Aziz; P E Oyer; S Strober; R Hoppe; H S Kaplan; E B Stinson; N E Shumway
Journal:  Transplantation       Date:  1981-12       Impact factor: 4.939

9.  Genomic biomarkers correlate with HLA-identical renal transplant tolerance.

Authors:  Joseph R Leventhal; James M Mathew; Daniel R Salomon; Sunil M Kurian; Manikkam Suthanthiran; Anat Tambur; John Friedewald; Lorenzo Gallon; Jane Charette; Josh Levitsky; Yashpal Kanwar; Michael Abecassis; Joshua Miller
Journal:  J Am Soc Nephrol       Date:  2013-06-20       Impact factor: 10.121

10.  Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance.

Authors:  T Wekerle; M H Sayegh; J Hill; Y Zhao; A Chandraker; K G Swenson; G Zhao; M Sykes
Journal:  J Exp Med       Date:  1998-06-15       Impact factor: 14.307
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  12 in total

Review 1.  Regulatory dendritic cells for human organ transplantation.

Authors:  Angus W Thomson; Diana M Metes; Mohamed B Ezzelarab; Dalia Raïch-Regué
Journal:  Transplant Rev (Orlando)       Date:  2019-05-13       Impact factor: 3.943

2.  Tolerogenic interactions between CD8+ dendritic cells and NKT cells prevent rejection of bone marrow and organ grafts.

Authors:  David Hongo; Xiaobin Tang; Xiangyue Zhang; Edgar G Engleman; Samuel Strober
Journal:  Blood       Date:  2017-01-17       Impact factor: 22.113

3.  The combination of mitomycin-induced blood cells with a temporary treatment of ciclosporin A prolongs allograft survival in vascularized composite allotransplantation.

Authors:  Christian Andreas Radu; Sebastian Fischer; Yannick Diehm; Otto Hetzel; Florian Neubrech; Laura Dittmar; Christian Kleist; Martha Maria Gebhard; Peter Terness; Ulrich Kneser; Jurij Kiefer
Journal:  Langenbecks Arch Surg       Date:  2017-08-19       Impact factor: 3.445

Review 4.  Extrarenal determinants of kidney filter function.

Authors:  Eunsil Hahm; Vasil Peev; Jochen Reiser
Journal:  Cell Tissue Res       Date:  2017-05-30       Impact factor: 5.249

5.  Haploidentical mixed chimerism cures autoimmunity in established type 1 diabetic mice.

Authors:  Yuqing Liu; Xiaoqi Wang; Yongping Zhu; Mingfeng Zhang; Ubaydah Nasri; Sharne S Sun; Stephen J Forman; Arthur D Riggs; Xi Zhang; Defu Zeng
Journal:  J Clin Invest       Date:  2020-12-01       Impact factor: 14.808

6.  Impact of Pretransplantation Renal Dysfunction on Outcomes after Allogeneic Hematopoietic Cell Transplantation.

Authors:  Nosha Farhadfar; Ajoy Dias; Tao Wang; Caitrin Fretham; Saurabh Chhabra; Hemant S Murthy; Larisa Broglie; Anita D'Souza; Shahinaz M Gadalla; Robert Peter Gale; Shahrukh Hashmi; A Samer Al-Homsi; Gerhard C Hildebrandt; Peiman Hematti; David Rizzieri; Lynette Chee; Hillard M Lazarus; Christopher Bredeson; Edgar A Jaimes; Amer Beitinjaneh; Asad Bashey; Tim Prestidge; Maxwell M Krem; David I Marks; Stefanie Benoit; Jean A Yared; Taiga Nishihori; Richard F Olsson; Cesar O Freytes; Edward Stadtmauer; Bipin N Savani; Mohamed L Sorror; Siddhartha Ganguly; John R Wingard; Marcelo Pasquini
Journal:  Transplant Cell Ther       Date:  2021-02-26

Review 7.  Transplantation Tolerance through Hematopoietic Chimerism: Progress and Challenges for Clinical Translation.

Authors:  Benedikt Mahr; Nicolas Granofszky; Moritz Muckenhuber; Thomas Wekerle
Journal:  Front Immunol       Date:  2017-12-22       Impact factor: 7.561

Review 8.  Enabling allogeneic therapies: CIRM-funded strategies for immune tolerance and immune evasion.

Authors:  Lisa C Kadyk; Ross M Okamura; Sohel Talib
Journal:  Stem Cells Transl Med       Date:  2020-06-25       Impact factor: 6.940

9.  Reversal of autoimmunity by mixed chimerism enables reactivation of β cells and transdifferentiation of α cells in diabetic NOD mice.

Authors:  Shanshan Tang; Mingfeng Zhang; Samuel Zeng; Yaxun Huang; Melissa Qin; Ubaydah Nasri; Pere Santamaria; Arthur D Riggs; Liang Jin; Defu Zeng
Journal:  Proc Natl Acad Sci U S A       Date:  2020-11-23       Impact factor: 11.205

Review 10.  Cyclophosphamide-Induced Tolerance in Allogeneic Transplantation: From Basic Studies to Clinical Application.

Authors:  Koji Kato; Ario Takeuchi; Koichi Akashi; Masatoshi Eto
Journal:  Front Immunol       Date:  2020-01-31       Impact factor: 8.786
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