Literature DB >> 2679631

Organization of the Ig VH locus in mice and humans.

U Krawinkel, T Christoph, T Blankenstein.   

Abstract

In order to assess the contribution of the germline VH gene repertoire to antibody diversity, many groups have studied the evolution and the organization of the immunoglobulin VH gene locus in mice and humans. Here, Ulrich Krawinkel, Thomas Christoph and Thomas Blankenstein review recent data on this subject and discuss the potential influence of gene organization on the activation of the VH gene repertoire during the development of the mammalian immune system.

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Year:  1989        PMID： 2679631     DOI： 10.1016/0167-5699(89)90191-6

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  12 in total

Review 1.  Mouse chromosome 12.

Authors:  P D'Eustachio
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

2.  Preferential utilization of conserved immunoglobulin heavy chain variable gene segments during human fetal life.

Authors:  H W Schroeder; J Y Wang
Journal:  Proc Natl Acad Sci U S A       Date:  1990-08       Impact factor: 11.205

Review 3.  The molecular biology of B-cell lymphoma: clinicopathologic implications.

Authors:  P M Kluin; J H van Krieken
Journal:  Ann Hematol       Date:  1991-04       Impact factor: 3.673

4.  A deletion map of the human immunoglobulin heavy chain variable region.

Authors:  M A Walter; H M Dosch; D W Cox
Journal:  J Exp Med       Date:  1991-08-01       Impact factor: 14.307

Review 5.  Mouse map of paralogous genes.

Authors:  J H Nadeau; M Kosowsky
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

6.  Evolution of immunoglobulin heavy chain variable region genes: a VH family can last for 150-200 million years or longer.

Authors:  E Andersson; T Matsunaga
Journal:  Immunogenetics       Date:  1995       Impact factor: 2.846

7.  Immunoglobulin light chain variable region gene sequences for human antibodies to Haemophilus influenzae type b capsular polysaccharide are dominated by a limited number of V kappa and V lambda segments and VJ combinations.

Authors:  E E Adderson; P G Shackelford; R A Insel; A Quinn; P M Wilson; W L Carroll
Journal:  J Clin Invest       Date:  1992-03       Impact factor: 14.808

8.  Monoclonal anti-VH141 antibodies that specifically recognize the heavy chain variable region of, and are closely related to, MOPC141 myeloma protein whose VH gene belongs to VHQ52 family.

Authors:  Y Minami; N Sakato; T Komori; S Kishimoto; H Sugiyama
Journal:  Immunology       Date:  1991-04       Impact factor: 7.397

9.  Evolutionary relationship between human and mouse immunoglobulin kappa light chain variable region genes.

Authors:  G Kroemer; A Helmberg; A Bernot; C Auffray; R Kofler
Journal:  Immunogenetics       Date:  1991       Impact factor: 2.846

10.  Germ line maintenance of the pseudogene donor pool for somatic immunoglobulin gene conversion in chickens.

Authors:  W T McCormack; E A Hurley; C B Thompson
Journal:  Mol Cell Biol       Date:  1993-02       Impact factor: 4.272
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