| Literature DB >> 26796136 |
Ryoto Hourai1, Masatoshi Miyamura1, Ryunosuke Tasaki1, Akiko Iwata1, Yoshihiro Takeda1, Hideaki Morita1, Nobuharu Hanaoka2, Jun Tanigawa1, Kensaku Shibata1, Atsushi Takeshita3, Mitsuhiro Kawano4, Yasuharu Sato5, Yoshinobu Hirose3, Nobukazu Ishizaka6.
Abstract
Immunoglobulin G4 (IgG4)-related disease is an emerging new clinicopathological disorder that is characterized by elevation of serum IgG4 levels and histological findings of IgG4-positive plasmacytic infiltration. IgG4-related disease may appear synchronously or metachronously in a wide variety of organs. The current patient was found to have pericardial effusion and retroperitoneal fibrosis. He was subsequently diagnosed with coronary artery stenosis. (18)F-FDG positron emission tomography showed enhanced FDG uptake in lymph nodes as well as pericardial and peri-aortic tissue. Histopathology of the mediastinal lymph node showed the infiltration of numerous IgG4-positive cells, leading to the diagnosis of IgG4-related lymphadenopathy with pericardial and periarterial involvement.Entities:
Keywords: Cardiovascular system; IgG4-related disease; Lymphadenopathy
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Year: 2016 PMID: 26796136 DOI: 10.1007/s00380-016-0794-1
Source DB: PubMed Journal: Heart Vessels ISSN: 0910-8327 Impact factor: 2.037