Literature DB >> 26795426

Affective instability and the course of bipolar depression: results from the STEP-BD randomised controlled trial of psychosocial treatment.

Jonathan P Stange1, Louisa G Sylvia1, Pedro Vieira da Silva Magalhães1, David J Miklowitz1, Michael W Otto1, Ellen Frank1, Christine Yim1, Michael Berk1, Darin D Dougherty1, Andrew A Nierenberg1, Thilo Deckersbach2.   

Abstract

BACKGROUND: Little is known about predictors of recovery from bipolar depression. AIMS: We investigated affective instability (a pattern of frequent and large mood shifts over time) as a predictor of recovery from episodes of bipolar depression and as a moderator of response to psychosocial treatment for acute depression.
METHOD: A total of 252 out-patients with DSM-IV bipolar I or II disorder and who were depressed enrolled in the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) and were randomised to one of three types of intensive psychotherapy for depression (n= 141) or a brief psychoeducational intervention (n= 111). All analyses were by intention-to-treat.
RESULTS: Degree of instability of symptoms of depression and mania predicted a lower likelihood of recovery and longer time until recovery, independent of the concurrent effects of symptom severity. Affective instability did not moderate the effects of psychosocial treatment on recovery from depression.
CONCLUSIONS: Affective instability may be a clinically relevant characteristic that influences the course of bipolar depression. © The Royal College of Psychiatrists 2015.

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Year:  2016        PMID: 26795426      PMCID: PMC4816971          DOI: 10.1192/bjp.bp.114.162073

Source DB:  PubMed          Journal:  Br J Psychiatry        ISSN: 0007-1250            Impact factor:   9.319


  57 in total

Review 1.  Mediators and moderators of treatment effects in randomized clinical trials.

Authors:  Helena Chmura Kraemer; G Terence Wilson; Christopher G Fairburn; W Stewart Agras
Journal:  Arch Gen Psychiatry       Date:  2002-10

2.  The role of psychotherapy in bipolar disorder.

Authors:  Sue D Lauder; Michael Berk; David J Castle; Seetal Dodd; Lesley Berk
Journal:  Med J Aust       Date:  2010-08-16       Impact factor: 7.738

3.  Analytic strategies for understanding affective (in)stability and other dynamic processes in psychopathology.

Authors:  Ulrich W Ebner-Priemer; Michael Eid; Nikolaus Kleindienst; Simon Stabenow; Timothy J Trull
Journal:  J Abnorm Psychol       Date:  2009-02

4.  Morbidity in 303 first-episode bipolar I disorder patients.

Authors:  Ross J Baldessarini; Paola Salvatore; Hari-Mandir Kaur Khalsa; Priscilla Gebre-Medhin; Harkaitz Imaz; Ana González-Pinto; Jesus Perez; Núria Cruz; Carlo Maggini; Mauricio Tohen
Journal:  Bipolar Disord       Date:  2010-05       Impact factor: 6.744

5.  A meta-analysis of cognitive deficits in euthymic patients with bipolar disorder.

Authors:  Lucy J Robinson; Jill M Thompson; Peter Gallagher; Utpal Goswami; Allan H Young; I Nicol Ferrier; P Brian Moore
Journal:  J Affect Disord       Date:  2006-03-06       Impact factor: 4.839

6.  Functional impairment and disability across mood states in bipolar disorder.

Authors:  Adriane R Rosa; María Reinares; Erin E Michalak; C Mar Bonnin; Brisa Sole; Carolina Franco; Mercè Comes; Carla Torrent; Flávio Kapczinski; Eduard Vieta
Journal:  Value Health       Date:  2010-12       Impact factor: 5.725

7.  A randomized controlled study of cognitive therapy for relapse prevention for bipolar affective disorder: outcome of the first year.

Authors:  Dominic H Lam; Edward R Watkins; Peter Hayward; Jenifer Bright; Kim Wright; Natalie Kerr; Gina Parr-Davis; Pak Sham
Journal:  Arch Gen Psychiatry       Date:  2003-02

Review 8.  Effectiveness and safety of adjunctive antidepressants in the treatment of bipolar depression: a review.

Authors:  Eiran Vadim Harel; Yechiel Levkovitz
Journal:  Isr J Psychiatry Relat Sci       Date:  2008       Impact factor: 0.481

9.  Affective instability: measuring a core feature of borderline personality disorder with ecological momentary assessment.

Authors:  Timothy J Trull; Marika B Solhan; Sarah L Tragesser; Seungmin Jahng; Phillip K Wood; Thomas M Piasecki; David Watson
Journal:  J Abnorm Psychol       Date:  2008-08

10.  The cognitive building blocks of emotion regulation: ability to update working memory moderates the efficacy of rumination and reappraisal on emotion.

Authors:  Madeline Lee Pe; Filip Raes; Peter Kuppens
Journal:  PLoS One       Date:  2013-07-18       Impact factor: 3.240

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  7 in total

Review 1.  Using ambulatory assessment to measure dynamic risk processes in affective disorders.

Authors:  Jonathan P Stange; Evan M Kleiman; Robin J Mermelstein; Timothy J Trull
Journal:  J Affect Disord       Date:  2019-08-19       Impact factor: 4.839

2.  Let your fingers do the talking: Passive typing instability predicts future mood outcomes.

Authors:  Jonathan P Stange; John Zulueta; Scott A Langenecker; Kelly A Ryan; Andrea Piscitello; Jenna Duffecy; Melvin G McInnis; Pete Nelson; Olusola Ajilore; Alex Leow
Journal:  Bipolar Disord       Date:  2018-03-08       Impact factor: 6.744

3.  The association between variability, intensity, and persistence of suicidal ideation and prospective suicidal behavior in the systematic treatment enhancement program for bipolar disorder (STEP-BD) study.

Authors:  Bartholt Bloomfield-Clagett; Dede K Greenstein; Carlos A Zarate; Elizabeth D Ballard
Journal:  Int J Bipolar Disord       Date:  2022-07-01

4.  Cognitive reappraisal attenuates the association between depressive symptoms and emotional response to stress during adolescence.

Authors:  Benjamin G Shapero; Jonathan P Stange; Brae Anne McArthur; Lyn Y Abramson; Lauren B Alloy
Journal:  Cogn Emot       Date:  2018-04-11

5.  A double-edged sword? Sub-types of psychological flexibility are associated with distinct psychiatric disorders.

Authors:  Denckla C A; Consedine N S; Chung W J; Stein M; Roche M; Blais M
Journal:  J Res Pers       Date:  2018-10-06

6.  Explaining why childhood abuse is a risk factor for poorer clinical course in bipolar disorder: a path analysis of 923 people with bipolar I disorder.

Authors:  Steven Marwaha; Paul M Briley; Amy Perry; Phillip Rankin; Arianna DiFlorio; Nick Craddock; Ian Jones; Matthew Broome; Katherine Gordon-Smith; Lisa Jones
Journal:  Psychol Med       Date:  2019-09-18       Impact factor: 7.723

7.  Developing "MinDag" - an app to capture symptom variation and illness mechanisms in bipolar disorder.

Authors:  Thomas D Bjella; Margrethe Collier Høegh; Stine Holmstul Olsen; Sofie R Aminoff; Elizabeth Barrett; Torill Ueland; Romain Icick; Ole A Andreassen; Mari Nerhus; Henrik Myhre Ihler; Marthe Hagen; Cecilie Busch-Christensen; Ingrid Melle; Trine Vik Lagerberg
Journal:  Front Med Technol       Date:  2022-07-22
  7 in total

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