Literature DB >> 26794872

The XEN of reprogramming.

Ergin Beyret1, Juan Carlos Izpisua Belmonte1.   

Abstract

Reprogramming to pluripotency has thus far required complex procedures involving nuclear transfer, cell fusion or genetic manipulation. Two recent papers from Hongkui Deng's group now show various cell types can be reprogrammed simply by chemicals through an extraembryonic endoderm-like phase instead of the primitive streak-like mesendoderm induced by Yamanaka factors.

Mesh：

Year:  2016        PMID： 26794872      PMCID： PMC4746615          DOI： 10.1038/cr.2016.9

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  12 in total

Review 1.  Nuclear reprogramming to a pluripotent state by three approaches.

Authors:  Shinya Yamanaka; Helen M Blau
Journal:  Nature       Date:  2010-06-10       Impact factor: 49.962

2.  Pluripotent stem cells induced from mouse neural stem cells and small intestinal epithelial cells by small molecule compounds.

Authors:  Junqing Ye; Jian Ge; Xu Zhang; Lin Cheng; Zhengyuan Zhang; Shan He; Yuping Wang; Hua Lin; Weifeng Yang; Junfang Liu; Yang Zhao; Hongkui Deng
Journal:  Cell Res       Date:  2015-12-25       Impact factor: 25.617

3.  A XEN-like State Bridges Somatic Cells to Pluripotency during Chemical Reprogramming.

Authors:  Yang Zhao; Ting Zhao; Jingyang Guan; Xu Zhang; Yao Fu; Junqing Ye; Jialiang Zhu; Gaofan Meng; Jian Ge; Susu Yang; Lin Cheng; Yaqin Du; Chaoran Zhao; Ting Wang; Linlin Su; Weifeng Yang; Hongkui Deng
Journal:  Cell       Date:  2015-12-10       Impact factor: 41.582

4.  Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds.

Authors:  Pingping Hou; Yanqin Li; Xu Zhang; Chun Liu; Jingyang Guan; Honggang Li; Ting Zhao; Junqing Ye; Weifeng Yang; Kang Liu; Jian Ge; Jun Xu; Qiang Zhang; Yang Zhao; Hongkui Deng
Journal:  Science       Date:  2013-07-18       Impact factor: 47.728

5.  Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

Authors:  Kazutoshi Takahashi; Shinya Yamanaka
Journal:  Cell       Date:  2006-08-10       Impact factor: 41.582

6.  Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation.

Authors:  Kotaro Ohnishi; Katsunori Semi; Takuya Yamamoto; Masahito Shimizu; Akito Tanaka; Kanae Mitsunaga; Keisuke Okita; Kenji Osafune; Yuko Arioka; Toshiyuki Maeda; Hidenobu Soejima; Hisataka Moriwaki; Shinya Yamanaka; Knut Woltjen; Yasuhiro Yamada
Journal:  Cell       Date:  2014-02-13       Impact factor: 41.582

7.  A molecular roadmap of reprogramming somatic cells into iPS cells.

Authors:  Jose M Polo; Endre Anderssen; Ryan M Walsh; Benjamin A Schwarz; Christian M Nefzger; Sue Mei Lim; Marti Borkent; Effie Apostolou; Sara Alaei; Jennifer Cloutier; Ori Bar-Nur; Sihem Cheloufi; Matthias Stadtfeld; Maria Eugenia Figueroa; Daisy Robinton; Sridaran Natesan; Ari Melnick; Jinfang Zhu; Sridhar Ramaswamy; Konrad Hochedlinger
Journal:  Cell       Date:  2012-12-21       Impact factor: 41.582

Review 8.  Dynamic Pluripotent Stem Cell States and Their Applications.

Authors:  Jun Wu; Juan Carlos Izpisua Belmonte
Journal:  Cell Stem Cell       Date:  2015-11-05       Impact factor: 24.633

9.  An alternative pluripotent state confers interspecies chimaeric competency.

Authors:  Jun Wu; Daiji Okamura; Mo Li; Keiichiro Suzuki; Chongyuan Luo; Li Ma; Yupeng He; Zhongwei Li; Chris Benner; Isao Tamura; Marie N Krause; Joseph R Nery; Tingting Du; Zhuzhu Zhang; Tomoaki Hishida; Yuta Takahashi; Emi Aizawa; Na Young Kim; Jeronimo Lajara; Pedro Guillen; Josep M Campistol; Concepcion Rodriguez Esteban; Pablo J Ross; Alan Saghatelian; Bing Ren; Joseph R Ecker; Juan Carlos Izpisua Belmonte
Journal:  Nature       Date:  2015-05-06       Impact factor: 49.962

10.  Conversion from mouse embryonic to extra-embryonic endoderm stem cells reveals distinct differentiation capacities of pluripotent stem cell states.

Authors:  Lily T Y Cho; Sissy E Wamaitha; Isheng J Tsai; Jérôme Artus; Richard I Sherwood; Roger A Pedersen; Anna-Katerina Hadjantonakis; Kathy K Niakan
Journal:  Development       Date:  2012-07-12       Impact factor: 6.868
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  2 in total

Review 1.  Elixir of Life: Thwarting Aging With Regenerative Reprogramming.

Authors:  Ergin Beyret; Paloma Martinez Redondo; Aida Platero Luengo; Juan Carlos Izpisua Belmonte
Journal:  Circ Res       Date:  2018-01-05       Impact factor: 17.367

2.  Characterisation of extraembryonic endoderm-like cells from mouse embryonic fibroblasts induced using chemicals alone.

Authors:  Xia He; Guangfan Chi; Meiying Li; Jinying Xu; Lihong Zhang; Yaolin Song; Lina Wang; Yulin Li
Journal:  Stem Cell Res Ther       Date:  2020-04-16       Impact factor: 6.832
  2 in total

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