Literature DB >> 26794746

Structural characterization of an acidic Epimedium polysaccharide and its immune-enhancement activity.

Yi Wu1, Youying Li2, Chang Liu2, Entao Li2, Zhenzhen Gao2, Cui Liu3, Wei Gu2, Yee Huang2, Jiaguo Liu2, Deyun Wang2, Yuanliang Hu4.   

Abstract

One acidic polysaccharide named EPS-1 was isolated from the aqueous extract of the leaves of Epimedium acuminatum Franch. It may be composed of 1,4-linked α-d-GalpA, 1,3,4-linked α-d-GalpA, 1,6-linked β-d-Galp and terminal α-l-Rhap residues in a molar ratio of 11.0:1.0:1.0:1.0 by chemical and spectroscopic analysis. EPS-1 possessed immune modulation effects on peripheral T lymphocyte and immature chBM-DCs such as promoting the proliferation and cytokine secretion of these cells and increasing the phagocytosis ability of immature chBM-DCs.
Copyright © 2015 Elsevier Ltd. All rights reserved.

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Keywords:  Epimedium polysaccharide; Immature chBM-DCs; Immune modulation activity; Lymphocyte; Structural characterization; Trifluoroacetic acid (PubChem CID: 6422); d-Fructose (PubChem CID: 5984); d-Galactose (PubChem CID: 6036); d-Galacturonic acid (PubChem CID: 439215); d-Glucose (PubChem CID: 5793); d-Glucuronic acid (PubChem CID: 94715); d-Mannose (PubChem CID: 18950); d-Xylose (PubChem CID: 135191); l-Arabinose (PubChem CID: 439195); l-Rhamnose (PubChem CID: 25310)

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Year:  2015        PMID: 26794746     DOI: 10.1016/j.carbpol.2015.11.014

Source DB:  PubMed          Journal:  Carbohydr Polym        ISSN: 0144-8617            Impact factor:   9.381


  2 in total

1.  Structural Characterization and Immunoenhancing Effects of a Polysaccharide from the Soft Coral Lobophytum sarcophytoides.

Authors:  Xueqin Cao; Qian Zhang; Yanglu Zhu; Siju Li; Ying Cai; Pei Li; Deliang Liu; Yun Leng; Simin Ye; Zengmei Xu; Hao Li; Baochun Shen; Qiongfeng Liao; Lan Liu; Zhiyong Xie
Journal:  Mar Biotechnol (NY)       Date:  2022-02-17       Impact factor: 3.619

2.  Multifunctional Nanoparticles Encapsulating Astragalus Polysaccharide and Gold Nanorods in Combination with Focused Ultrasound for the Treatment of Breast Cancer.

Authors:  Jie Xiong; Binglei Jiang; Yong Luo; Jianzhong Zou; Xuan Gao; Die Xu; Yan Du; Lan Hao
Journal:  Int J Nanomedicine       Date:  2020-06-12
  2 in total

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