| Literature DB >> 26792714 |
Luca Dellafiora1, Alessio Perotti2, Gianni Galaverna1, Annamaria Buschini2, Chiara Dall'Asta3.
Abstract
In the matter of foodborne mycotoxins, beside a number of regulated compounds, regulations are totally missing for phase-II plant metabolites--the toxicological knowledge of which is still in its infancy. Currently, zearalenone-14-glucoside is in the pipeline and its toxicological role is under a glowing scientific debate. In our work it clearly showed high toxicological concerns as it is prone to conversion to well-known toxic compounds (i.e. zearalenone and both zearalenol isomers) when exposed to breast cancer cells culture. The need of future risk assessment studies has been pointed out accordingly.Entities:
Keywords: Bioconversion; Human cell lines; Hydrolysis; Masked mycotoxins; Zearalenone
Mesh:
Substances:
Year: 2016 PMID: 26792714 DOI: 10.1016/j.toxicon.2016.01.053
Source DB: PubMed Journal: Toxicon ISSN: 0041-0101 Impact factor: 3.033