Literature DB >> 26792714

On the masked mycotoxin zearalenone-14-glucoside. Does the mask truly hide?

Luca Dellafiora1, Alessio Perotti2, Gianni Galaverna1, Annamaria Buschini2, Chiara Dall'Asta3.   

Abstract

In the matter of foodborne mycotoxins, beside a number of regulated compounds, regulations are totally missing for phase-II plant metabolites--the toxicological knowledge of which is still in its infancy. Currently, zearalenone-14-glucoside is in the pipeline and its toxicological role is under a glowing scientific debate. In our work it clearly showed high toxicological concerns as it is prone to conversion to well-known toxic compounds (i.e. zearalenone and both zearalenol isomers) when exposed to breast cancer cells culture. The need of future risk assessment studies has been pointed out accordingly.
Copyright © 2016 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Bioconversion; Human cell lines; Hydrolysis; Masked mycotoxins; Zearalenone

Mesh:

Substances:

Year:  2016        PMID: 26792714     DOI: 10.1016/j.toxicon.2016.01.053

Source DB:  PubMed          Journal:  Toxicon        ISSN: 0041-0101            Impact factor:   3.033


  10 in total

Review 1.  Do Plant-Bound Masked Mycotoxins Contribute to Toxicity?

Authors:  Silvia W Gratz
Journal:  Toxins (Basel)       Date:  2017-02-28       Impact factor: 4.546

2.  Metabolism of Zearalenone and Its Major Modified Forms in Pigs.

Authors:  Sabina B Binder; Heidi E Schwartz-Zimmermann; Elisabeth Varga; Gerlinde Bichl; Herbert Michlmayr; Gerhard Adam; Franz Berthiller
Journal:  Toxins (Basel)       Date:  2017-02-08       Impact factor: 4.546

3.  Degradation of Aflatoxins by Means of Laccases from Trametes versicolor: An In Silico Insight.

Authors:  Luca Dellafiora; Gianni Galaverna; Massimo Reverberi; Chiara Dall'Asta
Journal:  Toxins (Basel)       Date:  2017-01-01       Impact factor: 4.546

4.  Plant organ cultures as masked mycotoxin biofactories: Deciphering the fate of zearalenone in micropropagated durum wheat roots and leaves.

Authors:  Laura Righetti; Enrico Rolli; Gianni Galaverna; Michele Suman; Renato Bruni; Chiara Dall'Asta
Journal:  PLoS One       Date:  2017-11-16       Impact factor: 3.240

Review 5.  Modified Fusarium Mycotoxins in Cereals and Their Products-Metabolism, Occurrence, and Toxicity: An Updated Review.

Authors:  Marcin Bryła; Agnieszka Waśkiewicz; Edyta Ksieniewicz-Woźniak; Krystyna Szymczyk; Renata Jędrzejczak
Journal:  Molecules       Date:  2018-04-20       Impact factor: 4.411

Review 6.  Co-Occurrence and Combinatory Effects of Alternaria Mycotoxins and other Xenobiotics of Food Origin: Current Scenario and Future Perspectives.

Authors:  Francesco Crudo; Elisabeth Varga; Georg Aichinger; Gianni Galaverna; Doris Marko; Chiara Dall'Asta; Luca Dellafiora
Journal:  Toxins (Basel)       Date:  2019-11-03       Impact factor: 4.546

7.  Metabolic Profile, Bioavailability and Toxicokinetics of Zearalenone-14-Glucoside in Rats after Oral and Intravenous Administration by Liquid Chromatography High-Resolution Mass Spectrometry and Tandem Mass Spectrometry.

Authors:  Feifei Sun; Haiguang Tan; Yanshen Li; Marthe De Boevre; Sarah De Saeger; Jinhui Zhou; Yi Li; Zhenghua Rao; Shupeng Yang; Huiyan Zhang
Journal:  Int J Mol Sci       Date:  2019-11-03       Impact factor: 5.923

Review 8.  Updated Review of the Toxicity of Selected Fusarium Toxins and Their Modified Forms.

Authors:  Adam Pierzgalski; Marcin Bryła; Joanna Kanabus; Marta Modrzewska; Grażyna Podolska
Journal:  Toxins (Basel)       Date:  2021-10-29       Impact factor: 4.546

9.  Zearalenone-14-Glucoside Is Hydrolyzed to Zearalenone by β-Glucosidase in Extracellular Matrix to Exert Intracellular Toxicity in KGN Cells.

Authors:  Haonan Ruan; Yunyun Wang; Yong Hou; Jing Zhang; Jiashuo Wu; Fangqing Zhang; Ming Sui; Jiaoyang Luo; Meihua Yang
Journal:  Toxins (Basel)       Date:  2022-07-04       Impact factor: 5.075

10.  Development of a reliable UHPLC-MS/MS method for simultaneous determination of zearalenone and zearalenone-14-glucoside in various feed products.

Authors:  Zhiqi Zhang; Yaling Cai; Kai Fan; Qingwen Huang; Xiuying Zhao; Haojie Cao; Zhihui Zhao; Emmanuel K Tangni; Zheng Han
Journal:  Front Chem       Date:  2022-08-10       Impact factor: 5.545

  10 in total

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