Literature DB >> 26791697

Scientists in the dark after French clinical trial proves fatal.

Declan Butler, Ewen Callaway.   

Abstract

Mesh：

Substances：

Year:  2016        PMID： 26791697     DOI： 10.1038/nature.2016.19189

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


× No keyword cloud information.
  21 in total

1.  Human CNS barrier-forming organoids with cerebrospinal fluid production.

Authors:  Laura Pellegrini; Claudia Bonfio; Jessica Chadwick; Farida Begum; Mark Skehel; Madeline A Lancaster
Journal:  Science       Date:  2020-06-11       Impact factor: 47.728

2.  Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474.

Authors:  Annelot C M van Esbroeck; Antonius P A Janssen; Armand B Cognetta; Daisuke Ogasawara; Guy Shpak; Mark van der Kroeg; Vasudev Kantae; Marc P Baggelaar; Femke M S de Vrij; Hui Deng; Marco Allarà; Filomena Fezza; Zhanmin Lin; Tom van der Wel; Marjolein Soethoudt; Elliot D Mock; Hans den Dulk; Ilse L Baak; Bogdan I Florea; Giel Hendriks; Luciano De Petrocellis; Herman S Overkleeft; Thomas Hankemeier; Chris I De Zeeuw; Vincenzo Di Marzo; Mauro Maccarrone; Benjamin F Cravatt; Steven A Kushner; Mario van der Stelt
Journal:  Science       Date:  2017-06-09       Impact factor: 47.728

3.  Fatal Meningitis in Swine after Intrathecal Administration of Adeno-associated Virus Expressing Syngeneic Interleukin-10.

Authors:  Mark D Unger; Josef Pleticha; James E Collins; Anibal G Armien; Jennifer L Brazzell; Laura K Newman; Lukas F Heilmann; Jodi A Scholz; Timothy P Maus; Andreas S Beutler
Journal:  Mol Ther       Date:  2017-08-01       Impact factor: 11.454

Review 4.  Clinical trials for BET inhibitors run ahead of the science.

Authors:  Guillaume Andrieu; Anna C Belkina; Gerald V Denis
Journal:  Drug Discov Today Technol       Date:  2016-07-21

Review 5.  The emerging role of mass spectrometry-based proteomics in drug discovery.

Authors:  Felix Meissner; Jennifer Geddes-McAlister; Matthias Mann; Marcus Bantscheff
Journal:  Nat Rev Drug Discov       Date:  2022-03-29       Impact factor: 112.288

6.  Global Portrait of Protein Targets of Metabolites of the Neurotoxic Compound BIA 10-2474.

Authors:  Zhen Huang; Daisuke Ogasawara; Uthpala I Seneviratne; Armand B Cognetta; Christopher W Am Ende; Deane M Nason; Kimberly Lapham; John Litchfield; Douglas S Johnson; Benjamin F Cravatt
Journal:  ACS Chem Biol       Date:  2019-01-31       Impact factor: 5.100

7.  Implications of the BIA-102474-101 study for review of first-into-human clinical trials.

Authors:  Michael Eddleston; Adam F Cohen; David J Webb
Journal:  Br J Clin Pharmacol       Date:  2016-04       Impact factor: 4.335

Review 8.  Emerging targets for treating sulfur mustard-induced injuries.

Authors:  Shama Ahmad; Aftab Ahmad
Journal:  Ann N Y Acad Sci       Date:  2016-06-10       Impact factor: 5.691

9.  Phase 1 healthy volunteer willingness to participate and enrollment preferences.

Authors:  Stephanie C Chen; Ninet Sinaii; Gabriella Bedarida; Mark A Gregorio; Ezekiel Emanuel; Christine Grady
Journal:  Clin Trials       Date:  2017-08-02       Impact factor: 2.486

Review 10.  Positron Emission Tomography Imaging of the Endocannabinoid System: Opportunities and Challenges in Radiotracer Development.

Authors:  Lu Hou; Jian Rong; Ahmed Haider; Daisuke Ogasawara; Cassis Varlow; Michael A Schafroth; Linjing Mu; Jiefeng Gan; Hao Xu; Christopher J Fowler; Ming-Rong Zhang; Neil Vasdev; Simon Ametamey; Benjamin F Cravatt; Lu Wang; Steven H Liang
Journal:  J Med Chem       Date:  2020-12-30       Impact factor: 7.446
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.