Literature DB >> 26791117

Leukocytoclastic vasculitis associated with perforated diverticular disease.

Amalachukwu Michael Okpala1, Meera Joshi1, Brian Andrews1.   

Abstract

Leukocytoclastic vasculitis (LV) is a small vessel vasculitis associated with infections, connective tissue disease, malignancies and, rarely, gastrointestinal conditions. An association between LV and acute diverticulitis has not previously been reported. LV may be localised to the skin as a purpuric rash or might manifest with systemic involvement, such as of the joints, gastrointestinal tract or kidneys. Management of LV can be medical or surgical, based on the degree of systemic involvement. We present the case of a 56-year-old man with a 2-year history of a purpuric rash associated with diarrhoea, who presented acutely with abdominal pain. Imaging studies revealed sigmoid diverticulitis with a pericolic collection. Operative findings were purulent peritonitis secondary to perforated diverticular abscess, which was treated with a Hartmann's procedure. Postoperatively, the purpuric rash resolved rapidly on treatment with antibiotics and steroids. Histopathology of the resected bowel and skin punch biopsy confirmed sigmoid diverticulitis and LV, respectively. 2016 BMJ Publishing Group Ltd.

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Year:  2016        PMID: 26791117      PMCID: PMC4735271          DOI: 10.1136/bcr-2015-212310

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  4 in total

Review 1.  Management of leukocytoclastic vasculitis.

Authors:  C Sunderkötter; G Bonsmann; A Sindrilaru; T Luger
Journal:  J Dermatolog Treat       Date:  2005       Impact factor: 3.359

2.  Ulcerative colitis presenting as leukocytoclastic vasculitis of skin.

Authors:  Sabiye Akbulut; Ersan Ozaslan; Firdevs Topal; Levent Albayrak; Burcak Kayhan; Cumali Efe
Journal:  World J Gastroenterol       Date:  2008-04-21       Impact factor: 5.742

3.  Skin manifestations of inflammatory bowel disease.

Authors:  Brian L Huang; Stephanie Chandra; David Quan Shih
Journal:  Front Physiol       Date:  2012-02-06       Impact factor: 4.566

4.  Gastroenterology cases of cutaneous leukocytoclastic vasculitis.

Authors:  Cumali Karatoprak; Elif Arabaci; Kemal Yildiz; Mustafa Cakirca; Mehmet Ali Cikrikcioglu; Fatih Ergun; Ahmet Danalioglu; Orhan Kocaman; Hakan Senturk
Journal:  Case Rep Med       Date:  2013-10-22
  4 in total

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