Literature DB >> 26790841

Flavonoid metabolite 3-(3-hydroxyphenyl)propionic acid formed by human microflora decreases arterial blood pressure in rats.

Iveta Najmanová1, Jana Pourová1, Marie Vopršalová1, Veronika Pilařová2, Vladimír Semecký3, Lucie Nováková2, Přemysl Mladěnka1.   

Abstract

There are reports of positive effects of quercetin on cardiovascular pathologies, however, mainly due to its low biovailability, the mechanism remains elusive. Here, we report that one metabolite formed by human microflora (3-(3-hydroxyphenyl)propionic acid)relaxed isolated rat aorta and decreased arterial blood pressure in rats.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  Blood pressure; Flavonoid; Metabolite; Phenolic; Quercetin; Rat; Vascular

Mesh：

Substances：

Year:  2016        PMID： 26790841     DOI： 10.1002/mnfr.201500761

Source DB:  PubMed          Journal:  Mol Nutr Food Res        ISSN： 1613-4125            Impact factor:   5.914


  24 in total

Review 1.  The Interactions between Polyphenols and Microorganisms, Especially Gut Microbiota.

Authors:  Małgorzata Makarewicz; Iwona Drożdż; Tomasz Tarko; Aleksandra Duda-Chodak
Journal:  Antioxidants (Basel)       Date:  2021-01-28

Review 2.  Dietary Polyphenols Targeting Arterial Stiffness: Interplay of Contributing Mechanisms and Gut Microbiome-Related Metabolism.

Authors:  Tess De Bruyne; Bieke Steenput; Lynn Roth; Guido R Y De Meyer; Claudia Nunes Dos Santos; Kateřina Valentová; Maija Dambrova; Nina Hermans
Journal:  Nutrients       Date:  2019-03-08       Impact factor: 5.717

3.  The Effect of Silymarin Flavonolignans and Their Sulfated Conjugates on Platelet Aggregation and Blood Vessels Ex Vivo.

Authors:  Jana Pourová; Lenka Applová; Kateřina Macáková; Marie Vopršalová; Thomas Migkos; Roger Bentanachs; David Biedermann; Lucie Petrásková; Václav Tvrdý; Marcel Hrubša; Jana Karlíčková; Vladimír Křen; Kateřina Valentová; Přemysl Mladěnka
Journal:  Nutrients       Date:  2019-09-24       Impact factor: 5.717

Review 4.  The roles of gut microbiota and circadian rhythm in the cardiovascular protective effects of polyphenols.

Authors:  Andy W C Man; Ning Xia; Andreas Daiber; Huige Li
Journal:  Br J Pharmacol       Date:  2019-10-31       Impact factor: 8.739

Review 5.  Potential Implications of Quercetin in Autoimmune Diseases.

Authors:  Pan Shen; Weiji Lin; Xuan Deng; Xin Ba; Liang Han; Zhe Chen; Kai Qin; Ying Huang; Shenghao Tu
Journal:  Front Immunol       Date:  2021-06-23       Impact factor: 7.561

6.  Untargeted serum metabolomics and tryptophan metabolism profiling in type 2 diabetic patients with diabetic glomerulopathy.

Authors:  Fanliang Zhang; Ruixue Guo; Wen Cui; Li Wang; Jing Xiao; Jin Shang; Zhanzheng Zhao
Journal:  Ren Fail       Date:  2021-12       Impact factor: 2.606

7.  Metabolites of flavonoid compounds preserve indices of endothelial cell nitric oxide bioavailability under glucotoxic conditions.

Authors:  Y Qian; P V A Babu; J D Symons; T Jalili
Journal:  Nutr Diabetes       Date:  2017-09-11       Impact factor: 5.097

Review 8.  Antidiabetic Effects of Flavan-3-ols and Their Microbial Metabolites.

Authors:  Estefanía Márquez Campos; Linda Jakobs; Marie-Christine Simon
Journal:  Nutrients       Date:  2020-05-29       Impact factor: 5.717

Review 9.  Microbial Metabolites of Flavan-3-Ols and Their Biological Activity.

Authors:  Estefanía Márquez Campos; Peter Stehle; Marie-Christine Simon
Journal:  Nutrients       Date:  2019-09-20       Impact factor: 5.717

10.  Testing the Pharmacokinetic Interactions of 24 Colonic Flavonoid Metabolites with Human Serum Albumin and Cytochrome P450 Enzymes.

Authors:  Violetta Mohos; Eszter Fliszár-Nyúl; Beáta Lemli; Balázs Zoltán Zsidó; Csaba Hetényi; Přemysl Mladěnka; Pavel Horký; Milan Pour; Miklós Poór
Journal:  Biomolecules       Date:  2020-03-06
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