Literature DB >> 26790675

Delayed diagnosis of anorectal malformations (ARM): causes and consequences in a resource-constrained environment.

S Govender1,2, R Wiersma3,4.   

Abstract

PURPOSE: Delay in diagnosis or referral of patients with an anorectal malformation (ARM) is associated with significant morbidity and mortality. We describe the frequency and consequences of delay in recognition or referral of patients with ARM. Our study aims to determine whether the source healthcare facility affects the timing of diagnosis and to identify modifiable factors that may expedite diagnosis and referral.
METHODS: Retrospective study of patients referred to a pediatric surgical service with a newly diagnosed ARM between July 2002 and December 2010. Data retrieved included patient demographics, perinatal history, time of diagnosis, clinical findings, management, and morbidity and mortality. Delay was defined as diagnosis after 24 h of birth or transfer to the tertiary referral centre more than 24 h after diagnosis.
RESULTS: 273 patients (186 males, 87 females) were referred during the study period. Delays were seen in 158 (57.9%) patients with morbidity in 58 (36.7%, p < 0.001) and mortality in 9 (5.7%, p = 0.008). Delay was more frequent amongst babies born in community health centres (CHCs) than in hospitals (90.5 vs. 55.1%, p = 0.002). The median age at diagnosis was 3 days (range 2 days to 5 years).
CONCLUSION: There is a need for staff education, particularly in CHCs, concerning routine neonatal examination and normal perineal anatomy. Girls, in whom a decompressive fistula is often present, are at particular risk of diagnostic delay. Delay causes increased morbidity and mortality.

Entities:  

Keywords:  Anorectal malformation; Delay; Morbidity; Mortality

Mesh:

Year:  2016        PMID: 26790675     DOI: 10.1007/s00383-016-3866-5

Source DB:  PubMed          Journal:  Pediatr Surg Int        ISSN: 0179-0358            Impact factor:   1.827


  12 in total

1.  Are we winning? Improving perinatal outcomes at a deeply rural district hospital in South Africa.

Authors:  C Benjamin Gaunt
Journal:  S Afr Med J       Date:  2010-01-29

2.  Delayed diagnosis of anorectal malformations: are current guidelines sufficient?

Authors:  Brooke E Wilson; Claire E Etheridge; Soundappan V S Soundappan; Andrew J A Holland
Journal:  J Paediatr Child Health       Date:  2010-03-22       Impact factor: 1.954

3.  Presentation of low anorectal malformations beyond the neonatal period.

Authors:  H L Kim; K W Gow; J G Penner; G K Blair; J J Murphy; E M Webber
Journal:  Pediatrics       Date:  2000-05       Impact factor: 7.124

4.  Delayed presentation of anorectal malformations: the possible associated morbidity and mortality.

Authors:  Almoutaz A Eltayeb
Journal:  Pediatr Surg Int       Date:  2010-07-03       Impact factor: 1.827

5.  Preliminary report on the International Conference for the Development of Standards for the Treatment of Anorectal Malformations.

Authors:  Alexander Holschneider; John Hutson; Albert Peña; Elhamy Beket; Subir Chatterjee; Arnold Coran; Michael Davies; Keith Georgeson; Jay Grosfeld; Devendra Gupta; Naomi Iwai; Dieter Kluth; Giuseppe Martucciello; Samuel Moore; Risto Rintala; E Durham Smith; D V Sripathi; Douglas Stephens; Sudipta Sen; Benno Ure; Sabine Grasshoff; Thomas Boemers; Feilin Murphy; Yunus Söylet; Martin Dübbers; Marc Kunst
Journal:  J Pediatr Surg       Date:  2005-10       Impact factor: 2.545

6.  Delayed diagnosis of imperforate anus: an unacceptable morbidity.

Authors:  Carmen Turowski; Jens Dingemann; John Gillick
Journal:  Pediatr Surg Int       Date:  2010-11       Impact factor: 1.827

7.  The spectrum of anorectal malformations in Africa.

Authors:  S W Moore; A Alexander; D Sidler; J Alves; G P Hadley; A Numanoglu; B Banieghbal; M Chitnis; D Birabwa-Male; B Mbuwayesango; A Hesse; K Lakhoo
Journal:  Pediatr Surg Int       Date:  2008-04-03       Impact factor: 1.827

8.  Delays in the diagnosis of anorectal malformations are common and significantly increase serious early complications.

Authors:  Richard M Lindley; Rang N Shawis; Julian P Roberts
Journal:  Acta Paediatr       Date:  2006-03       Impact factor: 2.299

Review 9.  Imperforate anus: long- and short-term outcome.

Authors:  Risto J Rintala; Mikko P Pakarinen
Journal:  Semin Pediatr Surg       Date:  2008-05       Impact factor: 2.754

Review 10.  Congenital anorectal malformations: anything new?

Authors:  Risto J Rintala
Journal:  J Pediatr Gastroenterol Nutr       Date:  2009-04       Impact factor: 2.839

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  1 in total

1.  Anorectal malformations, associated congenital anomalies and their investigation in a South African setting.

Authors:  Elmarie Vd Merwe; S Cox; A Numanoglu
Journal:  Pediatr Surg Int       Date:  2017-06-13       Impact factor: 1.827

  1 in total

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