| Literature DB >> 26789919 |
Ann Chahroudi1, Guido Silvestri2.
Abstract
T follicular helper (Tfh) cells provide crucial support to antigen-specific B cells. In this issue of Immunity, Schultz et al. (2016) report that circulating IL-21-producing CD4(+) T cells are phenotypically, transcriptionally, and functionally similar to lymphoid Tfh cells and that such HIV-specific Tfh cells were increased in RV144 trial vaccine recipients.Entities:
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Year: 2016 PMID: 26789919 DOI: 10.1016/j.immuni.2015.12.016
Source DB: PubMed Journal: Immunity ISSN: 1074-7613 Impact factor: 31.745