Literature DB >> 26789512

Tectal Lesions in Children: A Long-Term Follow-Up Volumetric Tumor Growth Analysis in Surgical and Nonsurgical Cases.

Amir Kershenovich1, Zmira Silman, David de Rungs, Korgun Koral, Lynn Gargan, Bradley Weprin.   

Abstract

BACKGROUND/AIMS: Different tectal masses have been described; most are low-grade gliomas. Only 20-30% of all lesions grow, as shown on follow-up MRIs, requiring surgical resection at some point. The aim of this study is to describe the experience of a single institution managing pediatric patients with tectal lesions.
METHODS: We retrospectively studied and analyzed 40 children with tectal lesions managed from 1990 to 2006; the mean age at diagnosis was 9.4 years. A volumetric classification was used to analyze tumor growth trends. More than 1 year of imaging follow-up was available for 23 patients. RESULTS AND
CONCLUSION: Medium- and large-volume-size lesions were associated with the need for surgery. About half of the nonsurgical lesions grew at least 50% over a period of 4.5 years and did not require surgical resection.
© 2016 S. Karger AG, Basel.

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Year:  2016        PMID: 26789512     DOI: 10.1159/000442795

Source DB:  PubMed          Journal:  Pediatr Neurosurg        ISSN: 1016-2291            Impact factor:   1.162


  1 in total

1.  Tectal glioma as a distinct diagnostic entity: a comprehensive clinical, imaging, histologic and molecular analysis.

Authors:  Anthony P Y Liu; Julie H Harreld; Lisa M Jacola; Madelyn Gero; Sahaja Acharya; Yahya Ghazwani; Shengjie Wu; Xiaoyu Li; Paul Klimo; Amar Gajjar; Jason Chiang; Ibrahim Qaddoumi
Journal:  Acta Neuropathol Commun       Date:  2018-09-25       Impact factor: 7.801

  1 in total

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