Literature DB >> 26788679

Comparison of a low Hartmann's procedure with low colorectal anastomosis with and without defunctioning ileostomy after radiotherapy for rectal cancer: results from a national registry.

F H W Jonker1, P J Tanis2, P P L O Coene3, L Gietelink4, E van der Harst3.   

Abstract

AIM: This study used a national registry to compare the outcome after a low Hartmann's procedure (LHP), defined as removal of most of the rectum to leave a short anorectal stump and an end colostomy, and low anterior resection (LA) with or without a diverting ileostomy (DI) in rectal cancer patients all of whom had received preoperative neoadjuvant radiotherapy (RT).
METHOD: Patients who underwent LHP or LA with or without DI for rectal cancer after RT between 2009 and 2013 were identified from the Dutch Surgical Colorectal Audit. The postoperative outcome was compared between the three groups and risk of complications, reoperation and mortality were analysed in a multivariable model.
RESULTS: The study included 4288 patients were included, of whom 27.8% underwent LHP, 20.2% LA and 52.0% LA with DI. Thirty-day mortality was higher after LHP (3.2% vs 1.3% and 1.3% for LA with or without DI, P < 0.001), but LHP was not an independent predictor of mortality in multivariable analysis. LHP and LA with DI were associated with a lower rate of abdominal infective complications (6.5% and 10.1% vs 16.2%, P < 0.001) and reoperation (7.3% and 8.1% vs 16.5%, P < 0.001). In multivariable analysis, LHP (OR 0.35, 95% CI 0.26-0.47) and LA with DI (OR 0.43, 95% CI 0.33-0.54) were associated with a lower risk of reoperation than LA alone. LHP was associated with a lower risk of any postoperative complication than LA with or without DI (OR 0.81, 95% CI 0.66-0.98).
CONCLUSION: LHP and LA with DI were associated with fewer infective complications and reoperations than LA alone. The rate of any complication was less after LHR than LA with or without DI. Colorectal Disease
© 2016 The Association of Coloproctology of Great Britain and Ireland.

Entities:  

Keywords:  Rectal cancer; end-colostomy; low anterior resection; radiotherapy; total mesorectal excision

Mesh:

Year:  2016        PMID: 26788679     DOI: 10.1111/codi.13281

Source DB:  PubMed          Journal:  Colorectal Dis        ISSN: 1462-8910            Impact factor:   3.788


  4 in total

1.  Low risk of intra-abdominal infections in rectal cancer patients treated with Hartmann's procedure: a report from a national registry.

Authors:  Ingvar Sverrisson; Maziar Nikberg; Abbas Chabok; Kenneth Smedh
Journal:  Int J Colorectal Dis       Date:  2018-01-21       Impact factor: 2.571

2.  The impact of age on rectal cancer treatment, complications and survival.

Authors:  Øystein Høydahl; Tom-Harald Edna; Athanasios Xanthoulis; Stian Lydersen; Birger Henning Endreseth
Journal:  BMC Cancer       Date:  2022-09-12       Impact factor: 4.638

3.  Assessment of the risk of permanent stoma after low anterior resection in rectal cancer patients.

Authors:  Marcin Zeman; Marek Czarnecki; Andrzej Chmielarz; Adam Idasiak; Maciej Grajek; Agnieszka Czarniecka
Journal:  World J Surg Oncol       Date:  2020-08-14       Impact factor: 2.754

4.  Does oncological outcome differ between restorative and nonrestorative low anterior resection in patients with primary rectal cancer?

Authors:  Sapho X Roodbeen; Robin D Blok; Wernard A Borstlap; Willem A Bemelman; Roel Hompes; Pieter J Tanis
Journal:  Colorectal Dis       Date:  2020-12-15       Impact factor: 3.788

  4 in total

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