Literature DB >> 26784844

Chemical probes: The many genes of drug mechanism.

Adam C Palmer1.   

Abstract

Mesh:

Year:  2016        PMID: 26784844     DOI: 10.1038/nchembio.2010

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN: 1552-4450            Impact factor:   15.040


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  10 in total

1.  An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules.

Authors:  Amrita Basu; Nicole E Bodycombe; Jaime H Cheah; Edmund V Price; Ke Liu; Giannina I Schaefer; Richard Y Ebright; Michelle L Stewart; Daisuke Ito; Stephanie Wang; Abigail L Bracha; Ted Liefeld; Mathias Wawer; Joshua C Gilbert; Andrew J Wilson; Nicolas Stransky; Gregory V Kryukov; Vlado Dancik; Jordi Barretina; Levi A Garraway; C Suk-Yee Hon; Benito Munoz; Joshua A Bittker; Brent R Stockwell; Dineo Khabele; Andrew M Stern; Paul A Clemons; Alykhan F Shamji; Stuart L Schreiber
Journal:  Cell       Date:  2013-08-29       Impact factor: 41.582

2.  Opposing effects of target overexpression reveal drug mechanisms.

Authors:  Adam C Palmer; Roy Kishony
Journal:  Nat Commun       Date:  2014-07-01       Impact factor: 14.919

3.  Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling.

Authors:  Ultan McDermott; Sreenath V Sharma; Lori Dowell; Patricia Greninger; Clara Montagut; Jennifer Lamb; Heidi Archibald; Raul Raudales; Angela Tam; Diana Lee; S Michael Rothenberg; Jeffrey G Supko; Raffaella Sordella; Lindsey E Ulkus; A John Iafrate; Shyamala Maheswaran; Ching Ni Njauw; Hensin Tsao; Lisa Drew; Jeff H Hanke; Xiao-Jun Ma; Mark G Erlander; Nathanael S Gray; Daniel A Haber; Jeffrey Settleman
Journal:  Proc Natl Acad Sci U S A       Date:  2007-12-06       Impact factor: 11.205

4.  Amsacrine and etoposide hypersensitivity of yeast cells overexpressing DNA topoisomerase II.

Authors:  J L Nitiss; Y X Liu; P Harbury; M Jannatipour; R Wasserman; J C Wang
Journal:  Cancer Res       Date:  1992-08-15       Impact factor: 12.701

Review 5.  Target identification and mechanism of action in chemical biology and drug discovery.

Authors:  Monica Schenone; Vlado Dančík; Bridget K Wagner; Paul A Clemons
Journal:  Nat Chem Biol       Date:  2013-04       Impact factor: 15.040

6.  Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset.

Authors:  Brinton Seashore-Ludlow; Matthew G Rees; Jaime H Cheah; Murat Cokol; Edmund V Price; Matthew E Coletti; Victor Jones; Nicole E Bodycombe; Christian K Soule; Joshua Gould; Benjamin Alexander; Ava Li; Philip Montgomery; Mathias J Wawer; Nurdan Kuru; Joanne D Kotz; C Suk-Yee Hon; Benito Munoz; Ted Liefeld; Vlado Dančík; Joshua A Bittker; Michelle Palmer; James E Bradner; Alykhan F Shamji; Paul A Clemons; Stuart L Schreiber
Journal:  Cancer Discov       Date:  2015-10-19       Impact factor: 39.397

7.  The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Authors:  Jordi Barretina; Giordano Caponigro; Nicolas Stransky; Kavitha Venkatesan; Adam A Margolin; Sungjoon Kim; Christopher J Wilson; Joseph Lehár; Gregory V Kryukov; Dmitriy Sonkin; Anupama Reddy; Manway Liu; Lauren Murray; Michael F Berger; John E Monahan; Paula Morais; Jodi Meltzer; Adam Korejwa; Judit Jané-Valbuena; Felipa A Mapa; Joseph Thibault; Eva Bric-Furlong; Pichai Raman; Aaron Shipway; Ingo H Engels; Jill Cheng; Guoying K Yu; Jianjun Yu; Peter Aspesi; Melanie de Silva; Kalpana Jagtap; Michael D Jones; Li Wang; Charles Hatton; Emanuele Palescandolo; Supriya Gupta; Scott Mahan; Carrie Sougnez; Robert C Onofrio; Ted Liefeld; Laura MacConaill; Wendy Winckler; Michael Reich; Nanxin Li; Jill P Mesirov; Stacey B Gabriel; Gad Getz; Kristin Ardlie; Vivien Chan; Vic E Myer; Barbara L Weber; Jeff Porter; Markus Warmuth; Peter Finan; Jennifer L Harris; Matthew Meyerson; Todd R Golub; Michael P Morrissey; William R Sellers; Robert Schlegel; Levi A Garraway
Journal:  Nature       Date:  2012-03-28       Impact factor: 49.962

8.  Systematic identification of genomic markers of drug sensitivity in cancer cells.

Authors:  Mathew J Garnett; Elena J Edelman; Sonja J Heidorn; Chris D Greenman; Anahita Dastur; King Wai Lau; Patricia Greninger; I Richard Thompson; Xi Luo; Jorge Soares; Qingsong Liu; Francesco Iorio; Didier Surdez; Li Chen; Randy J Milano; Graham R Bignell; Ah T Tam; Helen Davies; Jesse A Stevenson; Syd Barthorpe; Stephen R Lutz; Fiona Kogera; Karl Lawrence; Anne McLaren-Douglas; Xeni Mitropoulos; Tatiana Mironenko; Helen Thi; Laura Richardson; Wenjun Zhou; Frances Jewitt; Tinghu Zhang; Patrick O'Brien; Jessica L Boisvert; Stacey Price; Wooyoung Hur; Wanjuan Yang; Xianming Deng; Adam Butler; Hwan Geun Choi; Jae Won Chang; Jose Baselga; Ivan Stamenkovic; Jeffrey A Engelman; Sreenath V Sharma; Olivier Delattre; Julio Saez-Rodriguez; Nathanael S Gray; Jeffrey Settleman; P Andrew Futreal; Daniel A Haber; Michael R Stratton; Sridhar Ramaswamy; Ultan McDermott; Cyril H Benes
Journal:  Nature       Date:  2012-03-28       Impact factor: 49.962

9.  Correlating chemical sensitivity and basal gene expression reveals mechanism of action.

Authors:  Matthew G Rees; Brinton Seashore-Ludlow; Jaime H Cheah; Drew J Adams; Edmund V Price; Shubhroz Gill; Sarah Javaid; Matthew E Coletti; Victor L Jones; Nicole E Bodycombe; Christian K Soule; Benjamin Alexander; Ava Li; Philip Montgomery; Joanne D Kotz; C Suk-Yee Hon; Benito Munoz; Ted Liefeld; Vlado Dančík; Daniel A Haber; Clary B Clish; Joshua A Bittker; Michelle Palmer; Bridget K Wagner; Paul A Clemons; Alykhan F Shamji; Stuart L Schreiber
Journal:  Nat Chem Biol       Date:  2015-12-14       Impact factor: 15.040

10.  Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics.

Authors:  Luc de Waal; Timothy A Lewis; Matthew G Rees; Aviad Tsherniak; Xiaoyun Wu; Peter S Choi; Lara Gechijian; Christina Hartigan; Patrick W Faloon; Mark J Hickey; Nicola Tolliday; Steven A Carr; Paul A Clemons; Benito Munoz; Bridget K Wagner; Alykhan F Shamji; Angela N Koehler; Monica Schenone; Alex B Burgin; Stuart L Schreiber; Heidi Greulich; Matthew Meyerson
Journal:  Nat Chem Biol       Date:  2015-12-14       Impact factor: 15.040

  10 in total
  1 in total

1.  Knowledge-guided gene prioritization reveals new insights into the mechanisms of chemoresistance.

Authors:  Amin Emad; Junmei Cairns; Krishna R Kalari; Liewei Wang; Saurabh Sinha
Journal:  Genome Biol       Date:  2017-08-11       Impact factor: 13.583

  1 in total

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