Literature DB >> 26782947

Enantioselective cellular uptake of chiral semiconductor nanocrystals.

I V Martynenko1, V A Kuznetsova, I K Litvinov, A O Orlova, V G Maslov, A V Fedorov, A Dubavik, F Purcell-Milton, Yu K Gun'ko, A V Baranov.   

Abstract

The influence of the chirality of semiconductor nanocrystals, CdSe/ZnS quantum dots (QDs) capped with L- and D-cysteine, on the efficiency of their uptake by living Ehrlich Ascite carcinoma cells is studied by spectral- and time-resolved fluorescence microspectroscopy. We report an evident enantioselective process where cellular uptake of the L-Cys QDs is almost twice as effective as that of the D-Cys QDs. This finding paves the way for the creation of novel approaches to control the biological properties and behavior of nanomaterials in living cells.

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Year:  2016        PMID: 26782947     DOI: 10.1088/0957-4484/27/7/075102

Source DB:  PubMed          Journal:  Nanotechnology        ISSN: 0957-4484            Impact factor:   3.874


  3 in total

1.  Enantiopure polythiophene nanoparticles. Chirality dependence of cellular uptake, intracellular distribution and antimicrobial activity.

Authors:  Ilaria Elena Palamà; Francesca Di Maria; Mattia Zangoli; Stefania D'Amone; Giovanni Manfredi; Jonathan Barsotti; Guglielmo Lanzani; Luca Ortolani; Elisabetta Salatelli; Giuseppe Gigli; Giovanna Barbarella
Journal:  RSC Adv       Date:  2019-07-25       Impact factor: 3.361

2.  Completely Chiral Optical Force for Enantioseparation.

Authors:  Ivan D Rukhlenko; Nikita V Tepliakov; Anvar S Baimuratov; Semen A Andronaki; Yurii K Gun'ko; Alexander V Baranov; Anatoly V Fedorov
Journal:  Sci Rep       Date:  2016-11-09       Impact factor: 4.379

Review 3.  Shining light on chiral inorganic nanomaterials for biological issues.

Authors:  Yining Shao; Guilin Yang; Jiaying Lin; Xiaofeng Fan; Yue Guo; Wentao Zhu; Ying Cai; Huiyu Huang; Die Hu; Wei Pang; Yanjun Liu; Yiwen Li; Jiaji Cheng; Xiaoqian Xu
Journal:  Theranostics       Date:  2021-09-07       Impact factor: 11.556

  3 in total

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