Literature DB >> 26782686

Ionic liquid supported organotin reagents to prepare molecular imaging and therapy agents.

Holisoa Rajerison1, Djibril Faye2, Aurélia Roumesy1, Nicolas Louaisil3, Fabien Boeda3, Alain Faivre-Chauvet1, Jean-François Gestin1, Stéphanie Legoupy2.   

Abstract

Efficiency of ionic liquid supported organotin reagents in halodemetalation reaction has been investigated. High radiochemical yields of astatinated and iodinated compounds have been obtained using simple work-up procedure. This methodology represents a straightforward approach for the preparation of molecular imaging and therapy agents in nuclear medicine.

Entities:  

Mesh：

Substances：

Year:  2016        PMID： 26782686     DOI： 10.1039/c5ob02459e

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  3 in total

1.  Unexpected Behavior of the Heaviest Halogen Astatine in the Nucleophilic Substitution of Aryliodonium Salts.

Authors:  François Guérard; Yong-Sok Lee; Kwamena Baidoo; Jean-François Gestin; Martin W Brechbiel
Journal:  Chemistry       Date:  2016-06-15       Impact factor: 5.236

2.  Rapid Cu-Catalyzed [211At]Astatination and [125I]Iodination of Boronic Esters at Room Temperature.

Authors:  Sean W Reilly; Mehran Makvandi; Kuiying Xu; Robert H Mach
Journal:  Org Lett       Date:  2018-03-21       Impact factor: 6.005

3.  Bifunctional aryliodonium salts for highly efficient radioiodination and astatination of antibodies.

Authors:  F Guérard; L Navarro; Y-S Lee; A Roumesy; C Alliot; M Chérel; M W Brechbiel; J-F Gestin
Journal:  Bioorg Med Chem       Date:  2017-09-19       Impact factor: 3.641
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.