Literature DB >> 26782121

Detection of weak hydrogen bonding to fluoro and nitro groups in solution using H/D exchange.

C R Shugrue1, J R DeFrancisco, A J Metrano, B D Brink, R S Nomoto, B R Linton.   

Abstract

Hydrogen/deuterium (H/D) exchange can be a sensitive technique for measuring the strength of hydrogen bonding to neutral organic nitro and fluoro groups. The slower rates of reaction in comparison to suitable controls suggest that hydrogen bonding is present, albeit rather weak.

Entities:  

Year:  2016        PMID: 26782121     DOI: 10.1039/c5ob02360b

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  1 in total

1.  Structure-based virtual screening workflow to identify antivirals targeting HIV-1 capsid.

Authors:  Qinfang Sun; Avik Biswas; R S K Vijayan; Pierrick Craveur; Stefano Forli; Arthur J Olson; Andres Emanuelli Castaner; Karen A Kirby; Stefan G Sarafianos; Nanjie Deng; Ronald Levy
Journal:  J Comput Aided Mol Des       Date:  2022-03-09       Impact factor: 4.179

  1 in total

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