Literature DB >> 26782091

[Multiple abscesses after a cruise along the Latin American coast].

C Reynolds1, N Schofer2, E Zengin2, A W Lohse1, S Faiss3, S Schmiedel4,5.   

Abstract

We report a case of an extracutaneous involvement of pyoderma gangrenosum. The patient initially presented with multiple sterile abscesses of the skin, heart, prostate, and kidney. Extracutaneous involvement in pyoderma gangrenosum is very rare. Confirmation of the diagnosis was only possible after exclusion of other relevant differential diagnoses. Continuous search for microbes proved negative and after an empiric therapeutic attempt with prednisolone, the patient improved quickly. However, each time we reduced the steroids even in combination with methotrexate or with azathioprine the patient relapsed. Only after therapy with the tumor necrosis factor-α-inhibitor infliximab was permanent remission achieved.

Entities:  

Keywords:  Abscess, sterile; Extracutaneous affection; Prednisolone; Pyoderma gangrenosum; Tumor necrosis factor-alpha, inhibitor

Mesh:

Substances:

Year:  2016        PMID: 26782091     DOI: 10.1007/s00108-015-0004-8

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  8 in total

Review 1.  Diagnosis and treatment of pyoderma gangrenosum.

Authors:  Trevor Brooklyn; Giles Dunnill; Chris Probert
Journal:  BMJ       Date:  2006-07-22

2.  Infliximab for the treatment of pyoderma gangrenosum: a randomised, double blind, placebo controlled trial.

Authors:  T N Brooklyn; M G S Dunnill; A Shetty; J J Bowden; J D L Williams; C E M Griffiths; A Forbes; R Greenwood; C S Probert
Journal:  Gut       Date:  2005-09-27       Impact factor: 23.059

3.  [Management of pyoderma gangrenosum. An update on clinical features, diagnosis and therapy].

Authors:  L Trémezaygues; R Schmaltz; T Vogt; J Reichrath
Journal:  Hautarzt       Date:  2010-04       Impact factor: 0.751

Review 4.  Pyoderma gangrenosum: clinicopathologic correlation and proposed diagnostic criteria.

Authors:  W P Daniel Su; Mark D P Davis; Roger H Weenig; Frank C Powell; Harold O Perry
Journal:  Int J Dermatol       Date:  2004-11       Impact factor: 2.736

Review 5.  Pyoderma gangrenosum: a review.

Authors:  A Neil Crowson; Martin C Mihm; Cynthia Magro
Journal:  J Cutan Pathol       Date:  2003-02       Impact factor: 1.587

6.  Multiple cavitary pulmonary nodules in association with pyoderma gangrenosum: case report.

Authors:  Maraya de Jesus Semblano Bittencourt; Luciana Fontenele Brito Soares; Lilia Sampaio Lobato; Alexandre Dias Mançano; Helandro Stuart Castro Leandro; Diana Mendes da Fonseca
Journal:  An Bras Dermatol       Date:  2012 Mar-Apr       Impact factor: 1.896

Review 7.  Pyoderma gangrenosum--a review.

Authors:  Uwe Wollina
Journal:  Orphanet J Rare Dis       Date:  2007-04-15       Impact factor: 4.123

8.  A challenging diagnosis: case report of extensive pyoderma gangrenosum at multiple sites.

Authors:  Mingwei J Ye; Joshua Mingsheng Ye; Leonard Wu; Cameron P Keating; Wai-Ting Choi
Journal:  Clin Cosmet Investig Dermatol       Date:  2014-03-26
  8 in total
  1 in total

1.  Pyoderma gangrenosum and tumour necrosis factor alpha inhibitors: A semi-systematic review.

Authors:  Hakim Ben Abdallah; Karsten Fogh; Rikke Bech
Journal:  Int Wound J       Date:  2019-01-03       Impact factor: 3.315

  1 in total

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