Literature DB >> 2678162

Double blind study of a valerian preparation.

O Lindahl1, L Lindwall.   

Abstract

Valerian root contains two substances of special pharmacological interest--valepotriates and sesquiterpenes. The former, which has been used for standardization of the drug, is cytotoxic. The latter has no such effect. Both have sedative effects. A double blind test has been carried out on a preparation (VALERINA NATT) containing primarily sesquiterpenes. When compared with placebo it showed a good and significant effect on poor sleep (p less than 0.001). Forty-four percent reported perfect sleep and 89% reported improved sleep from the preparation. No side effects were observed.

Entities:  

Mesh:

Substances:

Year:  1989        PMID: 2678162     DOI: 10.1016/0091-3057(89)90082-8

Source DB:  PubMed          Journal:  Pharmacol Biochem Behav        ISSN: 0091-3057            Impact factor:   3.533


  12 in total

1.  Adverse reactions to watch for in patients using herbal remedies.

Authors:  R Ko
Journal:  West J Med       Date:  1999-09

2.  An evidence-based review of the 10 most commonly used herbs.

Authors:  C Mar; S Bent
Journal:  West J Med       Date:  1999-09

3.  The use of alternative therapies in treating children with attention deficit hyperactivity disorder.

Authors: 
Journal:  Paediatr Child Health       Date:  2002-12       Impact factor: 2.253

4.  Herbal Medicine: Is it an Alternative or an Unknown? A Brief Review of Popular Herbals Used by Patients in a Pain and Symptom Management Practice Setting.

Authors: 
Journal:  Curr Rev Pain       Date:  1999

Review 5.  Herbal products in Canada. How safe are they?

Authors:  A Kozyrskyj
Journal:  Can Fam Physician       Date:  1997-04       Impact factor: 3.275

Review 6.  Clinical management of patients with insomnia. The role of zopiclone.

Authors:  G Hajak; A Rodenbeck
Journal:  Pharmacoeconomics       Date:  1996       Impact factor: 4.981

7.  Effects of Valeriana officinalis extracts on [3H]flunitrazepam binding, synaptosomal [3H]GABA uptake, and hippocampal [3H]GABA release.

Authors:  J G Ortiz; J Nieves-Natal; P Chavez
Journal:  Neurochem Res       Date:  1999-11       Impact factor: 3.996

8.  The use of Valeriana officinalis (Valerian) in improving sleep in patients who are undergoing treatment for cancer: a phase III randomized, placebo-controlled, double-blind study (NCCTG Trial, N01C5).

Authors:  Debra L Barton; Pamela J Atherton; Brent A Bauer; Dennis F Moore; Bassam I Mattar; Beth I Lavasseur; Kendrith M Rowland; Robin T Zon; Nguyet A Lelindqwister; Gauri G Nagargoje; Timothy I Morgenthaler; Jeff A Sloan; Charles L Loprinzi
Journal:  J Support Oncol       Date:  2011 Jan-Feb

9.  Aqueous and Ethanolic Valeriana officinalis Extracts Change the Binding of Ligands to Glutamate Receptors.

Authors:  Lisa M Del Valle-Mojica; José M Cordero-Hernández; Giselle González-Medina; Igmeris Ramos-Vélez; Nairimer Berríos-Cartagena; Bianca A Torres-Hernández; José G Ortíz
Journal:  Evid Based Complement Alternat Med       Date:  2010-12-02       Impact factor: 2.629

10.  Teaching Evidence-Based Complementary and Alternative Medicine (EBCAM); changing behaviours in the face of reticence: a cross-over trial.

Authors:  Edward Mills; Taras Hollyer; Ron Saranchuk; Kumanan Wilson
Journal:  BMC Med Educ       Date:  2002-01-14       Impact factor: 2.463

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.