Domenico Albano1, Caterina Patti2, Ludovico La Grutta3, Francesco Agnello3, Emanuele Grassedonio3, Antonino Mulè2, Giorgio Cannizzaro4, Umberto Ficola5, Roberto Lagalla3, Massimo Midiri3, Massimo Galia3. 1. Department of Radiology, University of Palermo, Via del Vespro 127, Palermo 90127, Italy. Electronic address: albanodomenico@me.com. 2. Department of Hematology I, Azienda Ospedali Riuniti Villa Sofia-Cervello, Viale Strasburgo 233, Palermo 90146, Italy. 3. Department of Radiology, University of Palermo, Via del Vespro 127, Palermo 90127, Italy. 4. Department of Nuclear Medicine, Azienda Ospedali Riuniti Villa Sofia-Cervello, Viale Strasburgo 233, Palermo 90146, Italy. 5. Department of Nuclear Medicine, La Maddalena Hospital, Via San Lorenzo Colli 312/d, Palermo 90146, Italy.
Abstract
OBJECTIVES: To compare whole body-MRI (WB-MRI) with diffusion-weighted imaging and FDG-PET/CT in staging newly diagnosed FDG-avid lymphomas. METHODS: 68 patients (37 males, 31 females; median age 42 years; range 15-86 years) with histologically confirmed lymphoma (37 Classical Hodgkin, 16 Diffuse large B-cell, 10 Follicular, 5 Mantle cell) underwent both MRI and FDG-PET/CT before treatment. Ann Arbor stages obtained with WB-MRI and FDG-PET/CT were compared using Cohen's k statistics. Moreover WB-MRI and FDG-PET/CT stages were compared with the pathological stages obtained after the diagnostic iter using also bone marrow and available biopsies if clinically indicated. RESULTS: The agreement between WB-MRI and FDG-PET/CT was excellent. WB-MRI stage was equal to those of FDG-PET/CT in 62/68 patients (91.2%). There was an excellent agreement between WB-MRI stage and pathological stage (63/68 patients; 92.6%), and between FDG-PET/CT and pathological stage (64/68 patients; 94.1%). The differences between the stages were more frequent in the patients with Mantle cell lymphoma. CONCLUSIONS: WB-MRI can be considered as a promising technique for FDG-avid lymphoma staging.
OBJECTIVES: To compare whole body-MRI (WB-MRI) with diffusion-weighted imaging and FDG-PET/CT in staging newly diagnosed FDG-avid lymphomas. METHODS: 68 patients (37 males, 31 females; median age 42 years; range 15-86 years) with histologically confirmed lymphoma (37 Classical Hodgkin, 16 Diffuse large B-cell, 10 Follicular, 5 Mantle cell) underwent both MRI and FDG-PET/CT before treatment. Ann Arbor stages obtained with WB-MRI and FDG-PET/CT were compared using Cohen's k statistics. Moreover WB-MRI and FDG-PET/CT stages were compared with the pathological stages obtained after the diagnostic iter using also bone marrow and available biopsies if clinically indicated. RESULTS: The agreement between WB-MRI and FDG-PET/CT was excellent. WB-MRI stage was equal to those of FDG-PET/CT in 62/68 patients (91.2%). There was an excellent agreement between WB-MRI stage and pathological stage (63/68 patients; 92.6%), and between FDG-PET/CT and pathological stage (64/68 patients; 94.1%). The differences between the stages were more frequent in the patients with Mantle cell lymphoma. CONCLUSIONS: WB-MRI can be considered as a promising technique for FDG-avid lymphoma staging.
Authors: Massimo Galia; Domenico Albano; Alberto Bruno; Antonino Agrusa; Giorgio Romano; Giuseppe Di Buono; Francesco Agnello; Giuseppe Salvaggio; Ludovico La Grutta; Massimo Midiri; Roberto Lagalla Journal: Br J Radiol Date: 2017-07-13 Impact factor: 3.039
Authors: D Giambelluca; D Albano; E Giambelluca; A Bruno; F Panzuto; A Agrusa; G Di Buono; F Cannizzaro; Cesare Gagliardo; M Midiri; R Lagalla; G Salvaggio Journal: G Chir Date: 2017 Sep-Oct