Literature DB >> 26780462

Identification of DVT diseases using numerical simulations.

M Simão1, J M Ferreira2, J Mora-Rodriguez3, H M Ramos4.   

Abstract

This research provides useful insights for better diagnosis and understanding the vein blockage induced by a deep venous thrombosis and the occurrence of reverse flow in human veins, allowing a proper detection of serious diseases related to deep venous insufficiency. An arbitrary Lagrangian-Eulerian formulation is used in a coupled model (i.e. fluid and structure equations solved together), considering two domains, specifically the blood flow and the flexible structures (i.e. vein and valves). Computational fluid dynamics mathematical model based on finite element method, with special elements and boundary characterization, is addressed to find the best solution. This research presents a novel model to study the interaction between non-Newtonian laminar fluid flows, the blood, within nonlinear structures, the vein walls. Simulation results are validated using in vivo echo-Doppler measurements.

Entities:  

Keywords:  Arbitrary Lagrangian–Eulerian (ALE); Computational fluid dynamics (CFD); Deep venous thrombosis (DVT); Hemodynamics; Non-Newtonian fluid

Mesh:

Year:  2016        PMID: 26780462     DOI: 10.1007/s11517-015-1446-9

Source DB:  PubMed          Journal:  Med Biol Eng Comput        ISSN: 0140-0118            Impact factor:   2.602


  14 in total

1.  Numerical model of deep venous thrombosis detection using venous occlusion strain gauge plethysmography.

Authors:  I C Turner; M A McNally; B M O'Connell; E A Cooke; W G Kernohan; R A Mollan
Journal:  Med Biol Eng Comput       Date:  2000-05       Impact factor: 2.602

2.  The influence of the non-Newtonian properties of blood on the flow in large arteries: steady flow in a carotid bifurcation model.

Authors:  F J Gijsen; F N van de Vosse; J D Janssen
Journal:  J Biomech       Date:  1999-06       Impact factor: 2.712

3.  Modeling hemodynamics in an unoccluded and partially occluded inferior vena cava under rest and exercise conditions.

Authors:  Zhuyin Ren; Stephen L Wang; Michael A Singer
Journal:  Med Biol Eng Comput       Date:  2012-02-22       Impact factor: 2.602

4.  Yield stress of normal human blood as a function of endogenous fibrinogen.

Authors:  E W Merrill; C S Cheng; G A Pelletier
Journal:  J Appl Physiol       Date:  1969-01       Impact factor: 3.531

Review 5.  Reduction in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin. Overview of results of randomized trials in general, orthopedic, and urologic surgery.

Authors:  R Collins; A Scrimgeour; S Yusuf; R Peto
Journal:  N Engl J Med       Date:  1988-05-05       Impact factor: 91.245

6.  "Normal" thrombin generation.

Authors:  S Butenas; C van't Veer; K G Mann
Journal:  Blood       Date:  1999-10-01       Impact factor: 22.113

7.  The incidence of deep venous thrombosis in patients with superficial thrombophlebitis of the lower limbs.

Authors:  J O Jorgensen; K C Hanel; A M Morgan; J M Hunt
Journal:  J Vasc Surg       Date:  1993-07       Impact factor: 4.268

Review 8.  The blood coagulation cascade.

Authors:  Monica Schenone; Barbara C Furie; Bruce Furie
Journal:  Curr Opin Hematol       Date:  2004-07       Impact factor: 3.284

9.  Effect of non-newtonian behavior on hemodynamics of cerebral aneurysms.

Authors:  Carolyn Fisher; Jenn Stroud Rossmann
Journal:  J Biomech Eng       Date:  2009-09       Impact factor: 2.097

10.  Extension of Murray's law using a non-Newtonian model of blood flow.

Authors:  Rémi Revellin; François Rousset; David Baud; Jocelyn Bonjour
Journal:  Theor Biol Med Model       Date:  2009-05-15       Impact factor: 2.432

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  2 in total

1.  Effect of valve lesion on venous valve cycle: A modified immersed finite element modeling.

Authors:  Xiang Liu; Lisheng Liu
Journal:  PLoS One       Date:  2019-03-04       Impact factor: 3.240

2.  The role of valve stiffness in the insurgence of deep vein thrombosis.

Authors:  Zoe Schofield; Hosam Alden Baksamawi; Joana Campos; Alessio Alexiadis; Gerard B Nash; Alexander Brill; Daniele Vigolo
Journal:  Commun Mater       Date:  2020-09-16
  2 in total

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