PURPOSE OF REVIEW: In this review, we summarize the evidence with regard to the rationale of using nonhigh density lipoprotein cholesterol (non-HDL-C) as a cardiovascular disease (CVD) risk factor, in relation to low-density lipoprotein cholesterol (LDL-C) and apolipoprotein B (apoB). RECENT FINDINGS: In the 2015 National Lipid Association Annual Summary non-HDL-C is considered a coprimary target, apart from LDL-C. The other data published in the last 18 months about non-HDL-C support all the previous published data. There are no recent findings, which we deem to cause a change of the current opinion about non-HDL-C as a predictor for CVD. SUMMARY: The existing evidence supports the claim that non-HDL-C is superior to LDL-C in CVD risk estimation.
PURPOSE OF REVIEW: In this review, we summarize the evidence with regard to the rationale of using nonhigh density lipoprotein cholesterol (non-HDL-C) as a cardiovascular disease (CVD) risk factor, in relation to low-density lipoprotein cholesterol (LDL-C) and apolipoprotein B (apoB). RECENT FINDINGS: In the 2015 National Lipid Association Annual Summary non-HDL-C is considered a coprimary target, apart from LDL-C. The other data published in the last 18 months about non-HDL-C support all the previous published data. There are no recent findings, which we deem to cause a change of the current opinion about non-HDL-C as a predictor for CVD. SUMMARY: The existing evidence supports the claim that non-HDL-C is superior to LDL-C in CVD risk estimation.
Authors: Dirk Müller-Wieland; Lawrence A Leiter; Bertrand Cariou; Alexia Letierce; Helen M Colhoun; Stefano Del Prato; Robert R Henry; Francisco J Tinahones; Lisa Aurand; Jaman Maroni; Kausik K Ray; Maja Bujas-Bobanovic Journal: Cardiovasc Diabetol Date: 2017-05-25 Impact factor: 9.951
Authors: Irene Alfaras; Sarah J Mitchell; Hector Mora; Darisbeth Rosario Lugo; Alessandra Warren; Ignacio Navas-Enamorado; Vickie Hoffmann; Christopher Hine; James R Mitchell; David G Le Couteur; Victoria C Cogger; Michel Bernier; Rafael de Cabo Journal: NPJ Aging Mech Dis Date: 2017-11-20
Authors: Om P Ganda; Jorge Plutzky; Santosh K Sanganalmath; Maja Bujas-Bobanovic; Andrew Koren; Jonas Mandel; Alexia Letierce; Lawrence A Leiter Journal: Diabetes Obes Metab Date: 2018-07-02 Impact factor: 6.577