| Literature DB >> 26778839 |
Abstract
Many countries currently perform antibody screening for HTLV-1 infection in blood donors, and this intervention is likely cost-effective in preventing HTLV-1 related diseases in high prevalence countries. However, a number of high-income countries with low prevalence of HTLV-1 infection also perform universal HTLV-1 screening and debate has arisen regarding the cost-effectiveness of these strategies. Filter-based leukoreduction is likely to substantially reduce HTLV-1 transmission by removing infected lymphocytes, but actual laboratory data on its efficacy is currently lacking. Similarly, cost-effectiveness research on HTLV-1 prevention strategies is limited by poor data on prevalence, transmission efficacy and the cost of treating HTLV1 diseases.Entities:
Keywords: Blood transfusion; Dépistage immunologique; HTLV-1; Immunoassay; Prevention and control; Prévention et contrôle; Transfusion sanguine
Mesh:
Year: 2016 PMID: 26778839 PMCID: PMC5042452 DOI: 10.1016/j.tracli.2015.12.001
Source DB: PubMed Journal: Transfus Clin Biol ISSN: 1246-7820 Impact factor: 1.406