Maria H C V Catão1, Roniery O Costa2, Cassiano F W Nonaka1, Ricardo L C Albuquerque Junior3, Ivna R R S Costa4. 1. Postgraduate Program in Dentistry, State University of Paraíba, Campina Grande, PB Brazil. 2. Postgraduate Program in Dentistry, State University of Paraíba, Campina Grande, PB Brazil. Electronic address: ronierycosta07@gmail.com. 3. Postgraduate Program in Health and Environment, Tiradentes University, Aracaju, SE Brazil. 4. Postgraduate Program in Natural Resources, Federal University of Campina Grande, Campina Grande, PB Brazil.
Abstract
PURPOSE: The aim of this study was to evaluate the effects of green LED light on inflammatory cells in skin burns: a histological study in rats. METHODS: In this study, 40 rats were randomly divided into 2 groups: G1 - Control (CTR) and G2 - Green Led (LED). Immediately after injury, green light (60J/cm(2), 10s, λ520 at 550nm) was applied in a timely manner in the four coinciding points of the wound angles and at each point, the amount of 60J/cm (2) with a time of 10s was delivered, totaling 240J/cm(2) per session with 24h intervals until the day before animal sacrifice at 3, 7, 14 and 21 days with a lethal dose of intraperitoneal anesthetic. RESULTS: In the histological analysis, animals treated with green LED, from 7 days, showed a significant decrease (p<0.05) in inflammatory cells when compared to control group. CONCLUSIONS: Green LED light provides an anti-inflammatory effect on skin burns of rats.
PURPOSE: The aim of this study was to evaluate the effects of green LED light on inflammatory cells in skin burns: a histological study in rats. METHODS: In this study, 40 rats were randomly divided into 2 groups: G1 - Control (CTR) and G2 - Green Led (LED). Immediately after injury, green light (60J/cm(2), 10s, λ520 at 550nm) was applied in a timely manner in the four coinciding points of the wound angles and at each point, the amount of 60J/cm (2) with a time of 10s was delivered, totaling 240J/cm(2) per session with 24h intervals until the day before animal sacrifice at 3, 7, 14 and 21 days with a lethal dose of intraperitoneal anesthetic. RESULTS: In the histological analysis, animals treated with green LED, from 7 days, showed a significant decrease (p<0.05) in inflammatory cells when compared to control group. CONCLUSIONS: Green LED light provides an anti-inflammatory effect on skin burns of rats.
Authors: Thamyres Maria Silva Simões; José de Alencar Fernandes Neto; Tharcia Kiara Beserra de Oliveira; Cassiano Francisco Weege Nonaka; Maria Helena Chaves de Vasconcelos Catão Journal: Lasers Med Sci Date: 2019-03-28 Impact factor: 3.161
Authors: Thamyres Maria Silva Simões; José de Alencar Fernandes Neto; Cassiano Francisco Weege Nonaka; Maria Helena Chaves de Vasconcelos Catão Journal: Lasers Med Sci Date: 2022-03-02 Impact factor: 2.555