Literature DB >> 2677742

How the ear's works work.

A J Hudspeth1.   

Abstract

The senses of hearing and equilibrium depend on sensory receptors called hair cells which can detect motions of atomic dimensions and respond more than 100,000 times a second. Biophysical studies suggest that mechanical forces control the opening and closing of transduction channels by acting through elastic components in each hair cell's mechanoreceptive hair bundle. Other ion channels, as well as the mechanical and hydrodynamic properties of hair bundles, tune individual hair cells to particular frequencies of stimulation.

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Year:  1989        PMID: 2677742     DOI: 10.1038/341397a0

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  219 in total

1.  Nanometre-range acoustic sensitivity in male and female mosquitoes.

Authors:  M C Göpfert; D Robert
Journal:  Proc Biol Sci       Date:  2000-03-07       Impact factor: 5.349

2.  Auditory sensitivity provided by self-tuned critical oscillations of hair cells.

Authors:  S Camalet; T Duke; F Jülicher; J Prost
Journal:  Proc Natl Acad Sci U S A       Date:  2000-03-28       Impact factor: 11.205

3.  Mutant ion channel in cochlear hair cells causes deafness.

Authors:  L Trussell
Journal:  Proc Natl Acad Sci U S A       Date:  2000-04-11       Impact factor: 11.205

4.  Immunocytochemical and morphological evidence for intracellular self-repair as an important contributor to mammalian hair cell recovery.

Authors:  J L Zheng; G Keller; W Q Gao
Journal:  J Neurosci       Date:  1999-03-15       Impact factor: 6.167

5.  Putting ion channels to work: mechanoelectrical transduction, adaptation, and amplification by hair cells.

Authors:  A J Hudspeth; Y Choe; A D Mehta; P Martin
Journal:  Proc Natl Acad Sci U S A       Date:  2000-10-24       Impact factor: 11.205

6.  Hair cell recovery in mitotically blocked cultures of the bullfrog saccule.

Authors:  R A Baird; M D Burton; A Lysakowski; D S Fashena; R A Naeger
Journal:  Proc Natl Acad Sci U S A       Date:  2000-10-24       Impact factor: 11.205

7.  High-resolution structure of hair-cell tip links.

Authors:  B Kachar; M Parakkal; M Kurc; Y Zhao; P G Gillespie
Journal:  Proc Natl Acad Sci U S A       Date:  2000-11-21       Impact factor: 11.205

8.  Myosin-1c interacts with hair-cell receptors through its calmodulin-binding IQ domains.

Authors:  Janet L Cyr; Rachel A Dumont; Peter G Gillespie
Journal:  J Neurosci       Date:  2002-04-01       Impact factor: 6.167

9.  Ca2+ transport properties and determinants of anomalous mole fraction effects of single voltage-gated Ca2+ channels in hair cells from bullfrog saccule.

Authors:  Adrian Rodriguez-Contreras; Wolfgang Nonner; Ebenezer N Yamoah
Journal:  J Physiol       Date:  2002-02-01       Impact factor: 5.182

10.  Direct measurement of single-channel Ca(2+) currents in bullfrog hair cells reveals two distinct channel subtypes.

Authors:  A Rodriguez-Contreras; E N Yamoah
Journal:  J Physiol       Date:  2001-08-01       Impact factor: 5.182

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