Literature DB >> 26776745

The base-promoted synthesis of multisubstituted benzo[b][1,4]oxazepines.

Jinhai Shen1, Lulu Xue, Xing Lin, Guolin Cheng, Xiuling Cui.   

Abstract

A novel protocol to synthesize multisubstituted benzo[b][1,4]oxazepines from N-(2-haloaryl)enaminones has been developed. In this procedure, only 2 equiv. of Cs2CO3 was required. A variety of polysubstituted benzo[b][1,4]oxazepine derivatives were provided in up to 95% yield for 27 examples.

Entities:  

Year:  2016        PMID: 26776745     DOI: 10.1039/c5cc09877g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Facile Synthesis for Benzo-1,4-Oxazepine Derivatives by Tandem Transformation of C-N Coupling/C-H Carbonylation.

Authors:  Xiaojia Zhao; Jiong Zhang; Zeqin Zheng; Runsheng Xu
Journal:  Molecules       Date:  2016-12-30       Impact factor: 4.411

2.  PIDA-mediated intramolecular oxidative C-N bond formation for the direct synthesis of quinoxalines from enaminones.

Authors:  Hong Zhang; Jinhai Shen; Zhenhui Yang; Xiuling Cui
Journal:  RSC Adv       Date:  2019-03-07       Impact factor: 4.036

  2 in total

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