Xiaofei Wang1,2, Tengfei Xing1, Tao Wei1, Jingqiang Zhu1. 1. Department of Thyroid and Breast Surgery, West China Hospital, Sichuan University, Chendu, China. 2. Department of General Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Abstract
BACKGROUND: Consensus regarding the difference of postoperative hypoparathyroidism following completion thyroidectomy (CT) and total thyroidectomy (TT) has yet to be reached. We compare the occurrence of postoperative hypoparathyroidism between CT and TT for differentiated thyroid cancer (DTC), and explore the predictive factors for postoperative hypoparathyroidism. METHODS: We retrospectively reviewed 221 consecutive patients underwent CT or TT for DTC between February 2012 and March 2014. Patients' demographic and clinical data of the two groups were analyzed. RESULTS: There were 57 CTs and 164 TTs. Temporary hypoparathyroidism occurred in 12.3% (7 of 57) and 28.0% (46 of 164) of patients in the CT and TT groups, respectively. In univariate analysis, type of surgical procedure (CT or TT) and extent of central lymph node dissection (CND) (unilateral or bilateral) were significantly associated with the postoperative temporary hypoparathyroidism (P < 0.05). Multivariate analysis showed that only the extent of CND was an independent risk factor for temporary hypoparathyroidism. CONCLUSIONS: Although temporary hypoparathyroidism was lower in the CT group, our analysis indicates the difference is due to the extent of CND rather than type of surgical procedure (CT vs. TT). Only bilateral CND is an independent risk factor for temporary hypoparathyroidism after thyroidectomy. J. Surg. Oncol. 2016;113:522-525.
BACKGROUND: Consensus regarding the difference of postoperative hypoparathyroidism following completion thyroidectomy (CT) and total thyroidectomy (TT) has yet to be reached. We compare the occurrence of postoperative hypoparathyroidism between CT and TT for differentiated thyroid cancer (DTC), and explore the predictive factors for postoperative hypoparathyroidism. METHODS: We retrospectively reviewed 221 consecutive patients underwent CT or TT for DTC between February 2012 and March 2014. Patients' demographic and clinical data of the two groups were analyzed. RESULTS: There were 57 CTs and 164 TTs. Temporary hypoparathyroidism occurred in 12.3% (7 of 57) and 28.0% (46 of 164) of patients in the CT and TT groups, respectively. In univariate analysis, type of surgical procedure (CT or TT) and extent of central lymph node dissection (CND) (unilateral or bilateral) were significantly associated with the postoperative temporary hypoparathyroidism (P < 0.05). Multivariate analysis showed that only the extent of CND was an independent risk factor for temporary hypoparathyroidism. CONCLUSIONS: Although temporary hypoparathyroidism was lower in the CT group, our analysis indicates the difference is due to the extent of CND rather than type of surgical procedure (CT vs. TT). Only bilateral CND is an independent risk factor for temporary hypoparathyroidism after thyroidectomy. J. Surg. Oncol. 2016;113:522-525.
Authors: Juan J Díez; Emma Anda; Julia Sastre; Begoña Pérez Corral; Cristina Álvarez-Escolá; Laura Manjón; Miguel Paja; Marcel Sambo; Piedad Santiago Fernández; Concepción Blanco Carrera; Juan C Galofré; Elena Navarro; Carles Zafón; Eva Sanz; Amelia Oleaga; Orosia Bandrés; Sergio Donnay; Ana Megía; María Picallo; Cecilia Sánchez Ragnarsson; Gloria Baena-Nieto; José Carlos Fernández García; Beatriz Lecumberri; Manel Sahún de la Vega; Ana R Romero-Lluch; Pedro Iglesias Journal: Endocrine Date: 2019-07-17 Impact factor: 3.633