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Literature DB >> 26776190

PRECISION MEDICINE: DATA AND DISCOVERY FOR IMPROVED HEALTH AND THERAPY.

Alexander A Morgan¹, Sean D Mooney, Bruce J Aronow, Steven E Brenner.

Abstract

Rapid advances in personal, cohort, and population-scale data acquisition, such as via sequencing, proteomics, mass spectroscopy, biosensors, mobile health devices and social network activity and other apps are opening up new vistas for personalized health biomedical data collection, analysis and insight. To achieve the vaunted goals of precision medicine and go from measurement to clinical translation, substantial gains still need to be made in methods of data and knowledge integration, analysis, discovery and interpretation. In this session of the 2016 Pacific Symposium on Biocomputing, we present sixteen papers to help accomplish this for precision medicine.

Entities: Disease Species

Mesh：

Year: 2016 PMID： 26776190 PMCID： PMC5180448

Source DB: PubMed Journal: Pac Symp Biocomput ISSN： 2335-6928

14 in total

1. Opening up to precompetitive collaboration.

Authors: Jill S Altshuler; Erin Balogh; Anna D Barker; Stephen L Eck; Stephen H Friend; Geoffrey S Ginsburg; Roy S Herbst; Sharyl J Nass; Christopher M Streeter; John A Wagner
Journal: Sci Transl Med Date: 2010-10-06 Impact factor: 17.956

2. The DNA of a nation.

Authors: Vivien Marx
Journal: Nature Date: 2015-08-27 Impact factor: 49.962

3. A new initiative on precision medicine.

Authors: Francis S Collins; Harold Varmus
Journal: N Engl J Med Date: 2015-01-30 Impact factor: 91.245

4. Metcalfe's law and the biology information commons.

Authors: Stephen H Friend; Thea C Norman
Journal: Nat Biotechnol Date: 2013-04 Impact factor: 54.908

5. Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics.

Authors: Andrea Sottoriva; Inmaculada Spiteri; Sara G M Piccirillo; Anestis Touloumis; V Peter Collins; John C Marioni; Christina Curtis; Colin Watts; Simon Tavaré
Journal: Proc Natl Acad Sci U S A Date: 2013-02-14 Impact factor: 11.205

Review 6. Quality assurance in clinical trials--the role of pathology.

Authors: Christoph Röcken
Journal: Virchows Arch Date: 2015-10-01 Impact factor: 4.064

Review 7. The landscape of precision cancer medicine clinical trials in the United States.

Authors: Nitin Roper; Kristian D Stensland; Ryan Hendricks; Matthew D Galsky
Journal: Cancer Treat Rev Date: 2015-02-27 Impact factor: 12.111

8. PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations.

Authors: Joshua C Denny; Marylyn D Ritchie; Melissa A Basford; Jill M Pulley; Lisa Bastarache; Kristin Brown-Gentry; Deede Wang; Dan R Masys; Dan M Roden; Dana C Crawford
Journal: Bioinformatics Date: 2010-03-24 Impact factor: 6.937

9. Personal omics profiling reveals dynamic molecular and medical phenotypes.

Authors: Rui Chen; George I Mias; Jennifer Li-Pook-Than; Lihua Jiang; Hugo Y K Lam; Rong Chen; Elana Miriami; Konrad J Karczewski; Manoj Hariharan; Frederick E Dewey; Yong Cheng; Michael J Clark; Hogune Im; Lukas Habegger; Suganthi Balasubramanian; Maeve O'Huallachain; Joel T Dudley; Sara Hillenmeyer; Rajini Haraksingh; Donald Sharon; Ghia Euskirchen; Phil Lacroute; Keith Bettinger; Alan P Boyle; Maya Kasowski; Fabian Grubert; Scott Seki; Marco Garcia; Michelle Whirl-Carrillo; Mercedes Gallardo; Maria A Blasco; Peter L Greenberg; Phyllis Snyder; Teri E Klein; Russ B Altman; Atul J Butte; Euan A Ashley; Mark Gerstein; Kari C Nadeau; Hua Tang; Michael Snyder
Journal: Cell Date: 2012-03-16 Impact factor: 41.582

10. A groupwise association test for rare mutations using a weighted sum statistic.

Authors: Bo Eskerod Madsen; Sharon R Browning
Journal: PLoS Genet Date: 2009-02-13 Impact factor: 5.917

4 in total

1. PRECISION MEDICINE: DATA AND DISCOVERY FOR IMPROVED HEALTH AND THERAPY.

Authors: Alexander A Morgan; Dana C Crawford; Josh C Denny; Sean D Mooney; Bruce J Aronow; Steven E Brenner
Journal: Pac Symp Biocomput Date: 2017

2. The Asthma Mobile Health Study, a large-scale clinical observational study using ResearchKit.

Authors: Yu-Feng Yvonne Chan; Pei Wang; Linda Rogers; Nicole Tignor; Micol Zweig; Steven G Hershman; Nicholas Genes; Erick R Scott; Eric Krock; Marcus Badgeley; Ron Edgar; Samantha Violante; Rosalind Wright; Charles A Powell; Joel T Dudley; Eric E Schadt
Journal: Nat Biotechnol Date: 2017-03-13 Impact factor: 54.908

Review 3. Factors Associated With Willingness to Share Health Information: Rapid Review.

Authors: Turin Tc; Iffat Naeem; Hude Quan; Shaminder Singh; Nashit Chowdhury; Mohammad Chowdhury; Vineet Saini
Journal: JMIR Hum Factors Date: 2022-02-09

4. A system for automatically extracting clinical events with temporal information.

Authors: Zhijing Li; Chen Li; Yu Long; Xuan Wang
Journal: BMC Med Inform Decis Mak Date: 2020-08-20 Impact factor: 2.796

4 in total