Literature DB >> 26774910

Report of the Inaugural Meeting of the TFOS i(2) = initiating innovation Series: Targeting the Unmet Need for Dry Eye Treatment.

Wendy Chao1, Carlos Belmonte2, José M Benitez Del Castillo3, Anthony J Bron4, Harminder S Dua5, Kelly K Nichols6, Gary D Novack7, Stefan Schrader8, Mark D Willcox9, James S Wolffsohn10, David A Sullivan11.   

Abstract

On March 21, 2015, a meeting was held in London, United Kingdom, to address the progress in targeting the unmet need for dry eye disease (DED) treatment. The meeting, which launched the i(2) = initiating innovation series, was sponsored by the Tear Film & Ocular Surface Society (TFOS; www.TearFilm.org) and supported by Dompé. The TFOS i(2) meeting was designed to review advances in the understanding of DED since publication of the 2007 TFOS International Dry Eye WorkShop (DEWS) report, and to help launch the highly anticipated sequel, DEWS II. The meeting was structured to discuss the scope of the DED problem, to review the clinical challenges of DED, and to consider the treatment challenges of DED. This article provides a synopsis of the presentations of this TFOS i(2) meeting.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Clinical trials; Dry Eye WorkShop II (DEWS II); Tear Film & Ocular Surface Society; drug development; dry eye disease (DED); i(2) = initiating innovation series

Mesh:

Year:  2016        PMID: 26774910     DOI: 10.1016/j.jtos.2015.11.003

Source DB:  PubMed          Journal:  Ocul Surf        ISSN: 1542-0124            Impact factor:   5.033


  18 in total

1.  Ophthalmic community perception of new medication needs.

Authors:  William C Stewart; Jeanette A Stewart; Lindsay A Nelson
Journal:  Int J Ophthalmol       Date:  2018-05-18       Impact factor: 1.779

Review 2.  Corneal epithelial cells function as surrogate Schwann cells for their sensory nerves.

Authors:  Mary Ann Stepp; Gauri Tadvalkar; Raymond Hakh; Sonali Pal-Ghosh
Journal:  Glia       Date:  2016-11-23       Impact factor: 7.452

3.  The Effect of Solithromycin, a Cationic Amphiphilic Drug, on the Proliferation and Differentiation of Human Meibomian Gland Epithelial Cells.

Authors:  Yang Liu; Wendy R Kam; Prabhavathi Fernandes; David A Sullivan
Journal:  Curr Eye Res       Date:  2017-12-28       Impact factor: 2.424

4.  Focused ultrasound stimulation on meibomian glands for the treatment of evaporative dry eye.

Authors:  Gengxi Lu; Sumanth Gollapudi; Runze Li; Margaret L Pfeiffer; Preeya Mehta; Laiming Jiang; Sarah Hamm-Alvarez; Mark Humayun; Qifa Zhou; Sandy X Zhang-Nunes
Journal:  Exp Biol Med (Maywood)       Date:  2021-10-14

5.  Influence of Omega 3 and 6 Fatty Acids on Human Meibomian Gland Epithelial Cells.

Authors:  Yang Liu; Wendy R Kam; David A Sullivan
Journal:  Cornea       Date:  2016-08       Impact factor: 2.651

Review 6.  Tear Osmolarity in the Diagnosis of Systemic Dehydration and Dry Eye Disease.

Authors:  Anthony J Bron; Catherine Willshire
Journal:  Diagnostics (Basel)       Date:  2021-02-25

7.  Do Cyclosporine A, an IL-1 Receptor Antagonist, Uridine Triphosphate, Rebamipide, and/or Bimatoprost Regulate Human Meibomian Gland Epithelial Cells?

Authors:  Wendy R Kam; Yang Liu; Juan Ding; David A Sullivan
Journal:  Invest Ophthalmol Vis Sci       Date:  2016-08-01       Impact factor: 4.799

Review 8.  Invisible Shield: Review of the Corneal Epithelium as a Barrier to UV Radiation, Pathogens, and Other Environmental Stimuli.

Authors:  Hasan Bashir; John T Seykora; Vivian Lee
Journal:  J Ophthalmic Vis Res       Date:  2017 Jul-Sep

Review 9.  The Growing Need for Validated Biomarkers and Endpoints for Dry Eye Clinical Research.

Authors:  Neeta S Roy; Yi Wei; Eric Kuklinski; Penny A Asbell
Journal:  Invest Ophthalmol Vis Sci       Date:  2017-05-01       Impact factor: 4.799

10.  Effects of a warm compress containing menthol on the tear film in healthy subjects and dry eye patients.

Authors:  Reiko Arita; Naoyuki Morishige; Ichiro Sakamoto; Natsuko Imai; Yuko Shimada; Michihito Igaki; Atsushi Suzuki; Kouzo Itoh; Kazuo Tsubota
Journal:  Sci Rep       Date:  2017-04-05       Impact factor: 4.379

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