Literature DB >> 26774368

Interplay of autophagy and apoptosis during PRRSV infection of Marc145 cell.

Shuaifeng Li1, Ao Zhou1, Jiaxing Wang1, Shujun Zhang2.   

Abstract

Autophagy and apoptosis play essential roles 'in virus infection. Our study was performed to investigate the interplay between autophagy and apoptosis in PRRSV replication. In our present study, autophagy and apoptosis were induced by PRRSV infection. Viral replication was dampened/attenuated by autophagy deficient and potentiated by apoptosis inhibition. Furthermore, PRRSV replication was restored by apoptosis inhibition in autophagy deficient cells. Taken together, our findings unveil the functional relationship between autophagy and apoptosis during PRRSV replication.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Apoptosis; Autophagy; Marc145 cell; PRRSV

Mesh：

Substances：

Year:  2016        PMID： 26774368     DOI： 10.1016/j.meegid.2016.01.011

Source DB:  PubMed          Journal:  Infect Genet Evol        ISSN： 1567-1348            Impact factor:   3.342


  10 in total

Review 1.  The Interaction between Nidovirales and Autophagy Components.

Authors:  Yingying Cong; Pauline Verlhac; Fulvio Reggiori
Journal:  Viruses       Date:  2017-07-11       Impact factor: 5.048

2.  Concurrent infection with porcine reproductive and respiratory syndrome virus and Haemophilus parasuis in two types of porcine macrophages: apoptosis, production of ROS and formation of multinucleated giant cells.

Authors:  Lenka Kavanová; Katarína Matiašková; Lenka Levá; Hana Štěpánová; Kateřina Nedbalcová; Ján Matiašovic; Martin Faldyna; Jiří Salát
Journal:  Vet Res       Date:  2017-05-04       Impact factor: 3.683

3.  Porcine Epidemic Diarrhea Virus Induces Autophagy to Benefit Its Replication.

Authors:  Xiaozhen Guo; Mengjia Zhang; Xiaoqian Zhang; Xin Tan; Hengke Guo; Wei Zeng; Guokai Yan; Atta Muhammad Memon; Zhonghua Li; Yinxing Zhu; Bingzhou Zhang; Xugang Ku; Meizhou Wu; Shengxian Fan; Qigai He
Journal:  Viruses       Date:  2017-03-19       Impact factor: 5.048

4.  Newcastle disease virus-induced autophagy mediates antiapoptotic signaling responses in vitro and in vivo.

Authors:  Yinfeng Kang; Runyu Yuan; Bin Xiang; Xiaqiong Zhao; Pei Gao; Xu Dai; Ming Liao; Tao Ren
Journal:  Oncotarget       Date:  2017-05-25

5.  Global miRNA, lncRNA, and mRNA Transcriptome Profiling of Endometrial Epithelial Cells Reveals Genes Related to Porcine Reproductive Failure Caused by Porcine Reproductive and Respiratory Syndrome Virus.

Authors:  Kang Zhang; Lijiang Ge; Shasha Dong; Ying Liu; Dong Wang; Chunyan Zhou; Cai Ma; Yanchao Wang; Feng Su; Yunliang Jiang
Journal:  Front Immunol       Date:  2019-06-04       Impact factor: 7.561

6.  Involvement of PRRSV NSP3 and NSP5 in the autophagy process.

Authors:  Wei Zhang; Keren Chen; Yang Guo; Yaosheng Chen; Xiaohong Liu
Journal:  Virol J       Date:  2019-01-28       Impact factor: 4.099

Review 7.  Molecular and Cellular Mechanisms for PRRSV Pathogenesis and Host Response to Infection.

Authors:  Tong-Qing An; Jiang-Nan Li; Chia-Ming Su; Dongwan Yoo
Journal:  Virus Res       Date:  2020-04-18       Impact factor: 3.303

8.  PRRSV Promotes MARC-145 Cells Entry Into S Phase of the Cell Cycle to Facilitate Viral Replication via Degradation of p21 by nsp11.

Authors:  Xuexia Wen; Xinna Ge; Lei Zhou; Yongning Zhang; Xin Guo; Hanchun Yang
Journal:  Front Vet Sci       Date:  2021-03-24

9.  Porcine reproductive and respiratory syndrome virus triggers mitochondrial fission and mitophagy to attenuate apoptosis.

Authors:  Shuaifeng Li; Jiaxing Wang; Ao Zhou; Faheem Ahmed Khan; Lin Hu; Shujun Zhang
Journal:  Oncotarget       Date:  2016-08-30

10.  The tail domain of PRRSV NSP2 plays a key role in aggrephagy by interacting with 14-3-3ε.

Authors:  Shengliang Cao; Jiaqi Liu; Guofei Ding; Qingyuan Shao; Bin Wang; Yingchao Li; Jian Feng; Yuzhong Zhao; Sidang Liu; Yihong Xiao
Journal:  Vet Res       Date:  2020-08-18       Impact factor: 3.683
  10 in total

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