Miki Tobe1, Takahiro Nemoto2, Naohisa Tsujino1, Taiju Yamaguchi1, Naoyuki Katagiri1, Chiyo Fujii3, Masafumi Mizuno1. 1. Department of Neuropsychiatry, Toho University School of Medicine, Tokyo, Japan. 2. Department of Neuropsychiatry, Toho University School of Medicine, Tokyo, Japan. Electronic address: takahiro.nemoto@med.toho-u.ac.jp. 3. National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.
Abstract
BACKGROUND: Deficits of motivation have been considered to be a core feature of schizophrenia, and recent studies have begun to reveal the biological and psychological characteristics and mechanisms underlying the deficits in motivation in schizophrenia patients. The aims of the present study were to investigate the characteristics of motivation in schizophrenia patients using the General Causality Orientations Scale (GCOS), and the impacts of motivational orientations on the functional outcomes in schizophrenia patients. METHODS: A total of 53 outpatients with schizophrenia and 38 healthy controls were recruited for this study. The GCOS was used to assess individual tendencies in respect of three different motivational orientations: the autonomy, controlled, and impersonal orientations, corresponding to intrinsic motivation, extrinsic motivation, and amotivation, respectively. The cognitive functioning, psychiatric symptoms, social functioning, and quality of life of the subjects were also assessed. RESULTS: The score for autonomy orientation was significantly lower in the patient group than that in the control group, while no significant differences were found between the two groups in respect of the scores for the other two orientations. The autonomy orientation was associated with various clinical variables, and regression analysis identified as one of the variables with the highest predictive accuracy for social functioning. CONCLUSIONS: Intrinsic motivation measured by the GCOS in schizophrenia patients was significantly lower than that in healthy controls. The deficits of intrinsic motivation were broadly associated with the clinical features and were a determinant of social functioning. Development of treatments for enhancing intrinsic motivation would be essential for functional recovery in schizophrenia patients.
BACKGROUND: Deficits of motivation have been considered to be a core feature of schizophrenia, and recent studies have begun to reveal the biological and psychological characteristics and mechanisms underlying the deficits in motivation in schizophreniapatients. The aims of the present study were to investigate the characteristics of motivation in schizophreniapatients using the General Causality Orientations Scale (GCOS), and the impacts of motivational orientations on the functional outcomes in schizophreniapatients. METHODS: A total of 53 outpatients with schizophrenia and 38 healthy controls were recruited for this study. The GCOS was used to assess individual tendencies in respect of three different motivational orientations: the autonomy, controlled, and impersonal orientations, corresponding to intrinsic motivation, extrinsic motivation, and amotivation, respectively. The cognitive functioning, psychiatric symptoms, social functioning, and quality of life of the subjects were also assessed. RESULTS: The score for autonomy orientation was significantly lower in the patient group than that in the control group, while no significant differences were found between the two groups in respect of the scores for the other two orientations. The autonomy orientation was associated with various clinical variables, and regression analysis identified as one of the variables with the highest predictive accuracy for social functioning. CONCLUSIONS: Intrinsic motivation measured by the GCOS in schizophreniapatients was significantly lower than that in healthy controls. The deficits of intrinsic motivation were broadly associated with the clinical features and were a determinant of social functioning. Development of treatments for enhancing intrinsic motivation would be essential for functional recovery in schizophreniapatients.
Authors: Ishraq Siddiqui; Gary Remington; Sarah Saperia; Susana Da Silva; Paul J Fletcher; Aristotle N Voineskos; Konstantine K Zakzanis; George Foussias Journal: Schizophrenia (Heidelb) Date: 2022-10-21