| Literature DB >> 26771228 |
Andy S Tsai1, John M Curto1, Benjamin N Rocke1, Anne-Marie R Dechert-Schmitt1, Gajendrasingh K Ingle1, Vincent Mascitti1.
Abstract
The first described reaction between N-tosylhydrazone and SO2 is reported to provide alkyl sulfonamides in the presence of various amines. In this procedurally simple method, hydrazones of both unsaturated aldehydes and ketones proceed in moderate to excellent yields. Primary and secondary aliphatic amines are accommodated in this reaction, which provides a novel route to sulfonamides.Entities:
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Year: 2016 PMID： 26771228 DOI： 10.1021/acs.orglett.5b03545
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005