| Literature DB >> 26771113 |
Andrei I Tarasov1, Patrik Rorsman2.
Abstract
How is β-cell mass adjusted to changes in the functional insulin requirements? The answer to this question is central to the understanding of the causes and (potentially) the therapy of type 2 diabetes. In this issue of Cell Metabolism, El Ouaamari et al. (2016) report that increased production of the protease inhibitor SerpinB1 in the liver links insulin resistance to stimulation of β-cell proliferation.Entities:
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Year: 2016 PMID： 26771113 DOI： 10.1016/j.cmet.2015.12.011
Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287