Literature DB >> 26770597

Status of trace elements and antioxidants in premenopausal and postmenopausal phase of life: a comparative study.

Sabah Ansar1, Tayef Alhefdhi1, Ansari M Aleem2.   

Abstract

The aim of the study was to determine the extent of free radical damage in the form of oxidative stress, the antioxidant status and correlate with trace element levels in postmenopausal females as compared to premenopausal females. Participants between the ages of 30-60 years were recruited for the study and status of antioxidant enzymes and trace metals level was determined. The serum Calcium (Ca) levels after menopause was higher than that of the premenopausal group (P<0.001). The changes in copper (Cu) and Zinc (Zn) between the groups were not significant (p>0.05). In postmenopausal women, antioxidant enzymes like superoxide dismutase (SOD) and glutathione peroxidase (GPX), catalase (CAT) significantly decreased (P<0.001) in postmenopausal women showing oxidative stress in the cells. Concentrations of vitamin-C pointed out a significant decrease (P<0.05) in postmenopausal women when compared with premenopausal women.

Entities:  

Keywords:  Trace elements; menopause; oxidative stress

Year:  2015        PMID： 26770597      PMCID： PMC4694497     

Source DB:  PubMed          Journal:  Int J Clin Exp Med        ISSN： 1940-5901


  32 in total

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Journal:  Chem Phys Lipids       Date:  2000-04       Impact factor: 3.329

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3.  Comparative effects of estrogen, raloxifene and tamoxifen on endothelial dysfunction, inflammatory markers and oxidative stress in ovariectomized rats.

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Journal:  Life Sci       Date:  2015-01-24       Impact factor: 5.037

4.  Antioxidant status in experimental hyperthyroidism: effect of vitamin E supplementation.

Authors:  A Seven; O Seymen; S Hatemi; H Hatemi; G Yiğit; G Candan
Journal:  Clin Chim Acta       Date:  1996-12-09       Impact factor: 3.786

5.  Estrogen plus progestin increase superoxide dismutase and total antioxidant capacity in postmenopausal women.

Authors:  T C Unfer; C G Figueiredo; M M Zanchi; L H Maurer; D M Kemerich; M M F Duarte; C K Konopka; T Emanuelli
Journal:  Climacteric       Date:  2014-11-12       Impact factor: 3.005

6.  Citrus fruit supplementation reduces lipoprotein oxidation in young men ingesting a diet high in saturated fat: presumptive evidence for an interaction between vitamins C and E in vivo.

Authors:  D Harats; S Chevion; M Nahir; Y Norman; O Sagee; E M Berry
Journal:  Am J Clin Nutr       Date:  1998-02       Impact factor: 7.045

7.  Effects of oestradiol and oestroprogestin on erythrocyte antioxidative enzyme system activity in postmenopausal women.

Authors:  Grazyna Bednarek-Tupikowska; Urszula Tworowska; Iwona Jedrychowska; Barbara Radomska; Krzysztof Tupikowski; Bozena Bidzinska-Speichert; Andrzej Milewicz
Journal:  Clin Endocrinol (Oxf)       Date:  2006-04       Impact factor: 3.478

8.  Antioxidant micronutrients and the risk of renal cell carcinoma in the Women's Health Initiative cohort.

Authors:  Won Jin Ho; Michael S Simon; Vedat O Yildiz; James M Shikany; Ikuko Kato; Jennifer L Beebe-Dimmer; Jeremy P Cetnar; Cathryn H Bock
Journal:  Cancer       Date:  2014-10-09       Impact factor: 6.860

9.  The association between oxidative stress and bone mineral density according to menopausal status of Korean women.

Authors:  Young Joo Lee; Ji Yun Hong; Seung Chul Kim; Jong Kil Joo; Yong Jin Na; Kyu Sup Lee
Journal:  Obstet Gynecol Sci       Date:  2015-01-16

Review 10.  The role of oxidative stress in menopause.

Authors:  Sejal B Doshi; Ashok Agarwal
Journal:  J Midlife Health       Date:  2013-07
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  3 in total

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2.  Evaluation of Salivary and Serum Total Antioxidant Capacity and Lipid Peroxidation in Postmenopausal Women.

Authors:  Fatemeh Zovari; Hadi Parsian; Ali Bijani; Ameneh Moslemnezhad; Atena Shirzad
Journal:  Int J Dent       Date:  2020-11-17

3.  Assessment of Psychological Status and Oxidative Stress in Postmenopausal Women: A Cross-Sectional Study.

Authors:  Manju Chandankhede; Madhur Gupta; Smita Pakhmode
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  3 in total

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