Yu Zhou1, Xinghua Yang2, Ling Fan3, Yuanfang Zhu4, Yurong Jiang5, Zhen Li6, Guoping Xiong7, Jingxin Shen8, Zhihong Su9, Ping Wu10, Danrui Wang11, Xietong Wang1. 1. Department of Obstetrics, Shandong Province Hospital Jinan 250014, Shandong, China. 2. School of Public Health, Capital Medical University Beijing 100069, China. 3. Department of Obstetrics, Beijing Gynaecology and Obstetrics Hospital of Capital Medical University Beijing 100069, China. 4. Department of Obstetrics, The First Affiliated Hospital of Nanchang University Nanchang 330006, Jiangxi, China. 5. Department of Obstetrics, Maternal and Child Health Hospital of Hunan Province Changsha 410008, Hunan, China. 6. Department of Obstetrics, Xinqiao Hospital Chongqing 400037, Sichuan, China. 7. Department of Obstetrics, Wuhan Central Hospital Wuhan 430014, Hubei, China. 8. Department of Obstetrics, The Third Xiangya Hospital of Central-South University Changsha 410013, Hunan, China. 9. Department of Obstetrics, Lanzhou General Hospital of Chinese People's Liberation Army Lanzhou 730050, Gansu, China. 10. Department of Obstetrics, Chongqing Three Gorges Central Hospital Chongqing 404000, China. 11. Department of Obstetrics, The Second Affiliated Hospital of Xinjiang Medical University Urumqi, Xinjiang 830028, China.
Abstract
UNLABELLED: To evaluate the efficacy and safety of lactulose in the intervention treatment of postpartum women with constipation. METHODS: The study adopted the multicenter clinical survey with a big sample which enrolled 4781 valid questionnaires from postpartum women in 18 different districts. All of them were treated with lactulose oral solution. Their constipation-related symptoms and routine examination on blood, urine and stool were monitored before and after lactulose intervention. The treatment duration lasted 2 weeks and all the patients were followed for 4 weeks. RESULT: Their stool consistency, daily defecation frequencies, defecating time and dyschezia were improved significantly after lactulose intervention, and the good therapeutic effect was remained at the off-medication session. Furthermore, abnormal rate of each index in blood, urine and stool examination showed a decreased trend. CONCLUSION: Lactulose offered good therapeutic benefit and could be developed as an effective intervention to postpartum women with constipation.
UNLABELLED: To evaluate the efficacy and safety of lactulose in the intervention treatment of postpartum women with constipation. METHODS: The study adopted the multicenter clinical survey with a big sample which enrolled 4781 valid questionnaires from postpartum women in 18 different districts. All of them were treated with lactulose oral solution. Their constipation-related symptoms and routine examination on blood, urine and stool were monitored before and after lactulose intervention. The treatment duration lasted 2 weeks and all the patients were followed for 4 weeks. RESULT: Their stool consistency, daily defecation frequencies, defecating time and dyschezia were improved significantly after lactulose intervention, and the good therapeutic effect was remained at the off-medication session. Furthermore, abnormal rate of each index in blood, urine and stool examination showed a decreased trend. CONCLUSION:Lactulose offered good therapeutic benefit and could be developed as an effective intervention to postpartum women with constipation.
Authors: Marco Soligo; Stefano Salvatore; Anton V Emmanuel; Elena De Ponti; Marco Zoccatelli; Marina Cortese; Rodolfo Milani Journal: Am J Obstet Gynecol Date: 2006-04-21 Impact factor: 8.661
Authors: Catherine S Bradley; Colleen M Kennedy; Anne M Turcea; Satish S C Rao; Ingrid E Nygaard Journal: Obstet Gynecol Date: 2007-12 Impact factor: 7.661